Gene description for CCDC105
Gene name coiled-coil domain containing 105
Gene symbol CCDC105
Other names/aliases -
Species Homo sapiens
 Database cross references - CCDC105
ExoCarta ExoCarta_126402
Vesiclepedia VP_126402
Entrez Gene 126402
HGNC 26866
UniProt Q8IYK2  
 CCDC105 identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for CCDC105
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    flagellated sperm motility GO:0030317 ISS
Subcellular Localization
    sperm flagellum GO:0036126 ISS
    extracellular exosome GO:0070062 HDA
    axonemal B tubule inner sheath GO:0160112 ISS
 Experiment description of studies that identified CCDC105 in sEVs
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CCDC105
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BRAP  
Two-hybrid Homo sapiens
2 MAGEA11  
Two-hybrid Homo sapiens
3 MESDC2 23184
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which CCDC105 is involved
No pathways found





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