Experiment description of studies that identified Cnp in sEVs

1 Experiment ID 907 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample Colon cancer cells Sample name C26 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 33 MISEV standards ✔ EM|IEM Biophysical techniques ✔ Alix|TSG101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Western blotting Mass spectrometry PubMed ID 21136642     Organism Mus musculus Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Authors "Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J" Journal name PROTEOMICS_CL Publication year 2007 Sample Oligodendrocytes Sample name Oligodendrocytes Oli-neu Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.10-1.14 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] Western blotting Immunoelectron Microscopy

3 Experiment ID 908 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample T-cell lymphoma cells Sample name EL4 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for Cnp

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Tnik   Affinity Capture-MS Mus musculus 2 SNCA 6622 Affinity Capture-MS Homo sapiens 3 Hcn1   Affinity Capture-MS Mus musculus 4 Kctd13   Affinity Capture-MS Mus musculus 5 Pde4dip   Affinity Capture-MS Mus musculus 6 MAPT   Reconstituted Complex Homo sapiens 7 Dlg4   Affinity Capture-MS Mus musculus Affinity Capture-MS Mus musculus 8 Atg5   Affinity Capture-RNA Mus musculus 9 Htt   Affinity Capture-MS Mus musculus 10 Huwe1   Affinity Capture-MS Mus musculus 11 Inadl   Affinity Capture-MS Mus musculus Affinity Capture-Western Mus musculus Reconstituted Complex Mus musculus 12 Fancd2   Affinity Capture-MS Mus musculus 13 Ywhaz 22631 Affinity Capture-MS Mus musculus View the network

Pathways in which Cnp is involved

No pathways found