Gene description for CHODL
Gene name chondrolectin
Gene symbol CHODL
Other names/aliases C21orf68
MT75
PRED12
Species Homo sapiens
 Database cross references - CHODL
ExoCarta ExoCarta_140578
Vesiclepedia VP_140578
Entrez Gene 140578
HGNC 17807
MIM 607247
UniProt Q9H9P2  
 CHODL identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for CHODL
Molecular Function
    protein binding GO:0005515 IPI
    hyaluronic acid binding GO:0005540 IDA
    carbohydrate binding GO:0030246 IEA
Biological Process
    nervous system development GO:0007399 IEA
    muscle organ development GO:0007517 NAS
    positive regulation of axonogenesis GO:0050772 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
    centrosome GO:0005813 IDA
    cytosol GO:0005829 IDA
    perinuclear region of cytoplasm GO:0048471 IDA
 Experiment description of studies that identified CHODL in sEVs
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for CHODL
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AP3S1 1176
Affinity Capture-MS Homo sapiens
2 C2CD2L 9854
Two-hybrid Homo sapiens
3 NINJ2  
Two-hybrid Homo sapiens
4 FAM118B  
Affinity Capture-MS Homo sapiens
5 SGPL1 8879
Affinity Capture-MS Homo sapiens
6 KIAA1804  
Affinity Capture-MS Homo sapiens
7 SCGB1D1  
Two-hybrid Homo sapiens
8 UQCC1 55245
Affinity Capture-MS Homo sapiens
9 COL2A1 1280
Affinity Capture-MS Homo sapiens
10 ATP12A 479
Affinity Capture-MS Homo sapiens
11 RMND1 55005
Affinity Capture-MS Homo sapiens
12 GPD1L 23171
Affinity Capture-MS Homo sapiens
13 IGFBP5 3488
Two-hybrid Homo sapiens
14 EBP  
Two-hybrid Homo sapiens
15 TTK 7272
Affinity Capture-MS Homo sapiens
16 C16orf91  
Affinity Capture-MS Homo sapiens
17 LRRC16A 55604
Affinity Capture-MS Homo sapiens
18 GPR50  
Affinity Capture-MS Homo sapiens
19 CCDC51 79714
Affinity Capture-MS Homo sapiens
20 LPGAT1 9926
Affinity Capture-MS Homo sapiens
21 BCL2L2 599
Two-hybrid Homo sapiens
22 MDN1 23195
Affinity Capture-MS Homo sapiens
23 DOLK 22845
Two-hybrid Homo sapiens
24 BNIP2  
Two-hybrid Homo sapiens
25 RAD51C  
Affinity Capture-MS Homo sapiens
26 UMPS 7372
Affinity Capture-MS Homo sapiens
27 CXCL9  
Two-hybrid Homo sapiens
28 ATP7A 538
Affinity Capture-MS Homo sapiens
29 ZDHHC21  
Two-hybrid Homo sapiens
30 EIF2B4 8890
Affinity Capture-MS Homo sapiens
31 RRAGB 10325
Affinity Capture-MS Homo sapiens
32 HELLS 3070
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CHODL is involved
No pathways found





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