Gene description for IL34
Gene name	interleukin 34
Gene symbol	IL34
Other names/aliases	C16orf77 IL-34
Species	Homo sapiens
Database cross references - IL34
ExoCarta	ExoCarta_146433
Vesiclepedia	VP_146433
Entrez Gene	146433
HGNC	28529
MIM	612081
UniProt	Q6ZMJ4
IL34 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for IL34

Molecular Function     cytokine activity GO:0005125 IEA     macrophage colony-stimulating factor receptor binding GO:0005157 IBA     macrophage colony-stimulating factor receptor binding GO:0005157 IDA     protein binding GO:0005515 IPI     growth factor activity GO:0008083 IEA     identical protein binding GO:0042802 IPI Biological Process     positive regulation of protein phosphorylation GO:0001934 IDA     inflammatory response GO:0006954 IEA     positive regulation of cell population proliferation GO:0008284 IBA     positive regulation of cell population proliferation GO:0008284 IDA     positive regulation of gene expression GO:0010628 IEA     positive regulation of macrophage chemotaxis GO:0010759 IDA     positive regulation of MAP kinase activity GO:0043406 IDA     innate immune response GO:0045087 IEA     positive regulation of macrophage differentiation GO:0045651 IBA     positive regulation of macrophage differentiation GO:0045651 IDA     positive regulation of monocyte differentiation GO:0045657 IBA     positive regulation of monocyte differentiation GO:0045657 IDA     positive regulation of oligodendrocyte differentiation GO:0048714 ISS     positive regulation of protein tyrosine kinase activity GO:0061098 IDA     interleukin-34-mediated signaling pathway GO:0061514 IDA     microglial cell proliferation GO:0061518 IEA     positive regulation of macrophage proliferation GO:0120041 IDA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IDA