Gene description for ZNF169
Gene name zinc finger protein 169
Gene symbol ZNF169
Other names/aliases -
Species Homo sapiens
 Database cross references - ZNF169
ExoCarta ExoCarta_169841
Vesiclepedia VP_169841
Entrez Gene 169841
HGNC 12957
MIM 603404
UniProt Q14929  
 ZNF169 identified in sEVs derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for ZNF169
Molecular Function
    RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000977 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
 Experiment description of studies that identified ZNF169 in sEVs
1
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ZNF169
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KRTAP10-7  
Two-hybrid Homo sapiens
2 CENPB 1059
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 CCNDBP1 23582
Two-hybrid Homo sapiens
4 ZNF316  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 ZNF689  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 RPS3 6188
Affinity Capture-MS Homo sapiens
7 ZNF184  
Affinity Capture-MS Homo sapiens
8 SORL1 6653
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 MRPS35 60488
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 ZBTB24  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 MRPS11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 TRIM41 90933
Affinity Capture-MS Homo sapiens
13 ZNF445  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 RPS15 6209
Affinity Capture-MS Homo sapiens
15 ZKSCAN8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 MRPS33  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 NAT10 55226
Affinity Capture-MS Homo sapiens
18 TRIM26 7726
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 ZFR 51663
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 LTBP4 8425
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 RBAK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 HNRNPR 10236
Affinity Capture-MS Homo sapiens
23 ZBTB10 65986
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 STRBP 55342
Affinity Capture-MS Homo sapiens
25 SOX2  
Affinity Capture-MS Homo sapiens
26 ZNF45  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 RPL26L1 51121
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 CLTCL1 8218
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 TPD52 7163
Affinity Capture-MS Homo sapiens
30 SART3 9733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 TRIM28 10155
Affinity Capture-MS Homo sapiens
32 ZNF92  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 KRTAP10-6  
Two-hybrid Homo sapiens
34 HIC2 23119
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 CEP70  
Two-hybrid Homo sapiens
36 ZSCAN25  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 SOGA1 140710
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 USP7 7874
Affinity Capture-MS Homo sapiens
39 ZNF324  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
41 GZF1  
Affinity Capture-MS Homo sapiens
42 ZNF121  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 ZNF629 23361
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 ZYG11A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 PATZ1  
Affinity Capture-MS Homo sapiens
46 LRP1B 53353
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 ZNF865  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 STAU2 27067
Affinity Capture-MS Homo sapiens
49 MRPS9 64965
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 C10orf2 56652
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 GSG2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 CABP5  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ZNF169 is involved
PathwayEvidenceSource
Gene expression (Transcription) TAS Reactome
Generic Transcription Pathway TAS Reactome
RNA Polymerase II Transcription TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here