Gene description for Matr3
Gene name matrin 3
Gene symbol Matr3
Other names/aliases 1110061A14Rik
2810017I02Rik
AI841759
AW555618
D030046F20Rik
mKIAA0723
Species Mus musculus
 Database cross references - Matr3
ExoCarta ExoCarta_17184
Vesiclepedia VP_17184
Entrez Gene 17184
UniProt Q8K310  
 Matr3 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Matr3
Molecular Function
    RNA binding GO:0003723 IBA
    zinc ion binding GO:0008270 IEA
    miRNA binding GO:0035198 ISO
    miRNA binding GO:0035198 ISS
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
Biological Process
    blastocyst formation GO:0001825 IMP
    activation of innate immune response GO:0002218 IEA
    activation of innate immune response GO:0002218 ISO
    heart valve development GO:0003170 IMP
    ventricular septum development GO:0003281 IMP
    post-transcriptional regulation of gene expression GO:0010608 IEA
    post-transcriptional regulation of gene expression GO:0010608 ISO
    innate immune response GO:0045087 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nuclear matrix GO:0016363 IEA
    nuclear matrix GO:0016363 ISO
 Experiment description of studies that identified Matr3 in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Matr3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kctd13  
Affinity Capture-MS Mus musculus
2 Elf5  
Affinity Capture-MS Mus musculus
3 Pde4dip  
Affinity Capture-MS Mus musculus
4 Pou5f1  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
5 Tnik  
Affinity Capture-MS Mus musculus
6 Tsc1  
Affinity Capture-MS Mus musculus
7 Fmr1  
Affinity Capture-MS Mus musculus
8 Cebpa  
Affinity Capture-MS Mus musculus
9 MKRN1 23608
Affinity Capture-MS Homo sapiens
10 Mecp2  
Affinity Capture-MS Mus musculus
11 Ywhaz 22631
Affinity Capture-MS Mus musculus
12 Herc2  
Affinity Capture-MS Mus musculus
13 Fzr1  
Affinity Capture-MS Mus musculus
14 Mycbp2 105689
Affinity Capture-MS Mus musculus
15 Cyfip1 20430
Affinity Capture-MS Mus musculus
16 Unk  
Affinity Capture-RNA Mus musculus
17 Rnf2  
Affinity Capture-MS Mus musculus
18 Zbtb7b  
Affinity Capture-MS Mus musculus
19 Eed  
Affinity Capture-MS Mus musculus
20 Atxn1  
Proximity Label-MS Mus musculus
Affinity Capture-MS Mus musculus
21 Atg16l1  
Affinity Capture-MS Mus musculus
22 Fancd2  
Affinity Capture-MS Mus musculus
23 Ubr5  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Matr3 is involved
No pathways found





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