Gene description for Pld2
Gene name	phospholipase D2
Gene symbol	Pld2
Other names/aliases	PLD1C
Species	Mus musculus
Database cross references - Pld2
ExoCarta	ExoCarta_18806
Vesiclepedia	VP_18806
Entrez Gene	18806
UniProt	P97813
Pld2 identified in sEVs derived from the following tissue/cell type
Basophilic leukemia cells	20424270

Gene ontology annotations for Pld2

Molecular Function     phospholipase D activity GO:0004630 IBA     phospholipase D activity GO:0004630 IDA     phospholipase D activity GO:0004630 ISO     phospholipase D activity GO:0004630 TAS     protein kinase C binding GO:0005080 ISO     phosphatidylinositol binding GO:0035091 IEA Biological Process     response to hypoxia GO:0001666 ISO     G protein-coupled receptor internalization GO:0002031 IDA     phosphatidic acid biosynthetic process GO:0006654 IEA     receptor-mediated endocytosis GO:0006898 IDA     phospholipid catabolic process GO:0009395 IBA     phospholipid catabolic process GO:0009395 ISO     response to organic cyclic compound GO:0014070 ISO     lipid catabolic process GO:0016042 IEA     positive regulation of cell migration GO:0030335 ISO     neuron projection development GO:0031175 ISO     intracellular signal transduction GO:0035556 IEA     response to hydrogen peroxide GO:0042542 ISO     positive regulation of mast cell degranulation GO:0043306 ISO     response to peptide hormone GO:0043434 ISO     positive regulation of cell adhesion GO:0045785 ISO     positive regulation of receptor-mediated endocytosis GO:0048260 ISO     positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 ISO     regulation of vesicle-mediated transport GO:0060627 IBA Subcellular Localization     endoplasmic reticulum membrane GO:0005789 TAS     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     caveola GO:0005901 ISO     lamellipodium GO:0030027 ISO     cytoplasmic vesicle GO:0031410 IBA     brush border membrane GO:0031526 IDA     sarcolemma GO:0042383 ISO