Gene description for DHRSX
Gene name
dehydrogenase/reductase (SDR family) X-linked
Gene symbol
DHRSX
Other names/aliases
CXorf11 DHRS5X DHRS5Y DHRSXY DHRSY SDR46C1 SDR7C6
Species
Homo sapiens
Database cross references - DHRSX
ExoCarta
ExoCarta_207063
Vesiclepedia
VP_207063
Entrez Gene
207063
HGNC
18399
UniProt
Q8N5I4
DHRSX identified in sEVs derived from the following tissue/cell type
Retinal pigment epithelial cells
35333565
Retinal pigment epithelial cells
35333565
Gene ontology annotations for DHRSX
Experiment description of studies that identified DHRSX in sEVs
1
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for DHRSX
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
APP
351
Reconstituted Complex
Homo sapiens
2
TMEM31
Two-hybrid
Homo sapiens
3
GCNT3
9245
Two-hybrid
Homo sapiens
4
ATXN1
6310
Two-hybrid
Homo sapiens
5
APOC1
Two-hybrid
Homo sapiens
6
TMEM86B
Two-hybrid
Homo sapiens
7
TMEM56
Two-hybrid
Homo sapiens
8
TMEM14B
Two-hybrid
Homo sapiens
9
CIDEB
Two-hybrid
Homo sapiens
10
FAM134C
162427
Two-hybrid
Homo sapiens
11
HSD17B11
51170
Two-hybrid
Homo sapiens
12
C16orf58
64755
Two-hybrid
Homo sapiens
13
TMEM143
Two-hybrid
Homo sapiens
14
PGRMC2
10424
Two-hybrid
Homo sapiens
15
ZDHHC15
158866
Two-hybrid
Homo sapiens
16
CMTM5
Two-hybrid
Homo sapiens
17
FADS3
3995
Two-hybrid
Homo sapiens
18
ASPH
444
Two-hybrid
Homo sapiens
19
ZBED1
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
20
PIGP
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which DHRSX is involved
No pathways found