Gene description for Nav1
Gene name neuron navigator 1
Gene symbol Nav1
Other names/aliases 9530089B19
9930003A20Rik
C230080M11Rik
Pomfil3
Unc53h1
mKIAA1151
steerin-1
Species Mus musculus
 Database cross references - Nav1
ExoCarta ExoCarta_215690
Vesiclepedia VP_215690
Entrez Gene 215690
UniProt Q8CH77  
 Nav1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nav1
Molecular Function
    ATP hydrolysis activity GO:0016887 IEA
Biological Process
    microtubule bundle formation GO:0001578 IBA
    microtubule bundle formation GO:0001578 IDA
    neuron migration GO:0001764 IBA
    neuron migration GO:0001764 IMP
    nervous system development GO:0007399 IBA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    microtubule GO:0005874 IEA
    microtubule cytoskeleton GO:0015630 IBA
    microtubule cytoskeleton GO:0015630 IDA
    axon initial segment GO:0043194 IBA
    axon initial segment GO:0043194 IDA
 Experiment description of studies that identified Nav1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nav1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Trio  
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
2 Twist1  
Proximity Label-MS Mus musculus
3 Pde4dip  
Affinity Capture-MS Mus musculus
4 Ywhae 22627
Affinity Capture-MS Mus musculus
5 Kctd13  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Nav1 is involved
No pathways found





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