Gene description for Tjp2
Gene name	tight junction protein 2
Gene symbol	Tjp2
Other names/aliases	ZO-2
Species	Mus musculus
Database cross references - Tjp2
ExoCarta	ExoCarta_21873
Vesiclepedia	VP_21873
Entrez Gene	21873
UniProt	Q9Z0U1
Tjp2 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Tjp2

Molecular Function     protein binding GO:0005515 IPI     protein domain specific binding GO:0019904 ISO     protein-macromolecule adaptor activity GO:0030674 ISO     transmembrane transporter binding GO:0044325 ISO     cell adhesion molecule binding GO:0050839 IBA     protein tyrosine kinase binding GO:1990782 ISO Biological Process     negative regulation of tumor necrosis factor-mediated signaling pathway GO:0010804 IMP     homotypic cell-cell adhesion GO:0034109 ISO     cell-cell junction organization GO:0045216 IBA     intestinal absorption GO:0050892 ISO     establishment of endothelial intestinal barrier GO:0090557 IBA     establishment of endothelial intestinal barrier GO:0090557 ISO     regulation of membrane permeability GO:0090559 ISO     cell-cell adhesion GO:0098609 IBA     protein localization to cell-cell junction GO:0150105 IBA     positive regulation of blood-brain barrier permeability GO:1905605 IBA     positive regulation of blood-brain barrier permeability GO:1905605 ISO     negative regulation of osteoclast development GO:2001205 IMP Subcellular Localization     nucleus GO:0005634 IDA     nucleus GO:0005634 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     cell-cell junction GO:0005911 IDA     gap junction GO:0005921 ISO     bicellular tight junction GO:0005923 IBA     bicellular tight junction GO:0005923 ISO     cell surface GO:0009986 ISO     cell junction GO:0030054 IDA     cell-cell contact zone GO:0044291 ISO     tight junction GO:0070160 IDA