Gene description for Myof
Gene name myoferlin
Gene symbol Myof
Other names/aliases 2310004N10Rik
2310051D19Rik
E030042N20Rik
Fer1l3
Species Mus musculus
 Database cross references - Myof
ExoCarta ExoCarta_226101
Vesiclepedia VP_226101
Entrez Gene 226101
UniProt Q69ZN7  
 Myof identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Myof
Molecular Function
    phospholipid binding GO:0005543 IBA
    phospholipid binding GO:0005543 IMP
    phospholipid binding GO:0005543 ISO
    metal ion binding GO:0046872 IEA
Biological Process
    plasma membrane repair GO:0001778 IBA
    plasma membrane repair GO:0001778 IMP
    glycerol metabolic process GO:0006071 IGI
    regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 IMP
    T-tubule organization GO:0033292 IBA
    T-tubule organization GO:0033292 IGI
    cellular response to heat GO:0034605 IDA
    muscle cell development GO:0055001 IGI
    membrane fusion GO:0061025 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 ISO
    caveola GO:0005901 IDA
    cytoplasmic vesicle membrane GO:0030659 IEA
    cytoplasmic vesicle GO:0031410 ISO
    nuclear membrane GO:0031965 IEA
    centriolar satellite GO:0034451 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
 Experiment description of studies that identified Myof in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Myof
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Rpa1 68275
Co-fractionation Mus musculus
2 Nphs2  
Affinity Capture-MS Mus musculus
3 Rpa3  
Co-fractionation Mus musculus
4 Tmem173  
Proximity Label-MS Mus musculus
View the network image/svg+xml
 Pathways in which Myof is involved
No pathways found





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