Gene description for Add1
Gene name	adducin 1 (alpha)
Gene symbol	Add1
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Add1
ExoCarta	ExoCarta_24170
Vesiclepedia	VP_24170
Entrez Gene	24170
UniProt	Q63028
Add1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Add1

Molecular Function     actin binding GO:0003779 IEA     structural constituent of cytoskeleton GO:0005200 IEA     structural constituent of cytoskeleton GO:0005200 ISO     protein binding GO:0005515 IPI     calmodulin binding GO:0005516 IEA     spectrin binding GO:0030507 ISO     T cell receptor binding GO:0042608 IDA     protein homodimerization activity GO:0042803 ISO     protein heterodimerization activity GO:0046982 ISO     protein dimerization activity GO:0046983 ISO     actin filament binding GO:0051015 IBA     actin filament binding GO:0051015 ISO     RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 ISO Biological Process     cell morphogenesis GO:0000902 IEA     cell morphogenesis GO:0000902 ISO     in utero embryonic development GO:0001701 IEA     in utero embryonic development GO:0001701 ISO     monoatomic ion transport GO:0006811 NAS     cell volume homeostasis GO:0006884 IEA     cell volume homeostasis GO:0006884 ISO     cytoskeleton organization GO:0007010 IEA     cytoskeleton organization GO:0007010 TAS     hemoglobin metabolic process GO:0020027 IEA     hemoglobin metabolic process GO:0020027 ISO     erythrocyte differentiation GO:0030218 IEA     erythrocyte differentiation GO:0030218 ISO     negative regulation of actin filament polymerization GO:0030837 IMP     multicellular organism growth GO:0035264 IEA     multicellular organism growth GO:0035264 ISO     positive regulation of angiogenesis GO:0045766 IDA     positive regulation of endocytosis GO:0045807 IMP     homeostasis of number of cells within a tissue GO:0048873 IEA     homeostasis of number of cells within a tissue GO:0048873 ISO     barbed-end actin filament capping GO:0051016 IBA     barbed-end actin filament capping GO:0051016 ISO     actin filament bundle assembly GO:0051017 ISO     cellular response to calcium ion GO:0071277 IEA     cellular response to calcium ion GO:0071277 ISO     cellular response to retinoic acid GO:0071300 IDA     positive regulation of establishment of endothelial barrier GO:1903142 IBA     positive regulation of establishment of endothelial barrier GO:1903142 IEA     positive regulation of establishment of endothelial barrier GO:1903142 ISO     positive regulation of adherens junction organization GO:1903393 IBA     positive regulation of adherens junction organization GO:1903393 IEA     positive regulation of adherens junction organization GO:1903393 ISO Subcellular Localization     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 ISO     cytoskeleton GO:0005856 IBA     cytoskeleton GO:0005856 IEA     cytoskeleton GO:0005856 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     adherens junction GO:0005912 IBA     adherens junction GO:0005912 IEA     adherens junction GO:0005912 ISO     F-actin capping protein complex GO:0008290 ISO     postsynaptic density GO:0014069 IBA     membrane GO:0016020 ISO     nuclear body GO:0016604 IEA     nuclear body GO:0016604 ISO     dendrite GO:0030425 IDA     dendritic spine GO:0043197 IDA     synapse GO:0045202 IEA     synapse GO:0045202 ISO     perinuclear region of cytoplasm GO:0048471 IDA