Gene description for Tf
Gene name	transferrin
Gene symbol	Tf
Other names/aliases	Tfn Trf
Species	Rattus norvegicus
Database cross references - Tf
ExoCarta	ExoCarta_24825
Vesiclepedia	VP_24825
Entrez Gene	24825
UniProt	P12346
Tf identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Tf

Molecular Function     GTP binding GO:0005525 IEA     ferrous iron binding GO:0008198 ISO     ferric iron binding GO:0008199 IDA     enzyme binding GO:0019899 ISO     iron chaperone activity GO:0034986 ISO     transmembrane transporter binding GO:0044325 ISO     metal ion binding GO:0046872 IEA     transferrin receptor binding GO:1990459 ISO Biological Process     response to hypoxia GO:0001666 IEP     iron ion transport GO:0006826 IBA     iron ion transport GO:0006826 IDA     iron ion transport GO:0006826 IEA     iron ion transport GO:0006826 ISO     iron ion transport GO:0006826 TAS     intracellular iron ion homeostasis GO:0006879 ISO     intracellular iron ion homeostasis GO:0006879 TAS     apoptotic process GO:0006915 ISS     acute-phase response GO:0006953 IEP     actin filament organization GO:0007015 ISO     response to bacterium GO:0009617 ISO     response to lead ion GO:0010288 IEP     response to organic cyclic compound GO:0014070 IEP     antibacterial humoral response GO:0019731 IBA     osteoclast differentiation GO:0030316 ISO     positive regulation of myelination GO:0031643 IDA     positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 ISO     regulation of iron ion transport GO:0034756 ISO     positive regulation of phosphorylation GO:0042327 ISO     positive regulation of bone resorption GO:0045780 ISO     positive regulation of DNA-templated transcription GO:0045893 ISO     positive regulation of receptor-mediated endocytosis GO:0048260 ISO     multicellular organismal-level iron ion homeostasis GO:0060586 ISO     ERK1 and ERK2 cascade GO:0070371 ISO     positive regulation of oligodendrocyte progenitor proliferation GO:0070447 IDA     cellular response to iron ion GO:0071281 ISO     cellular response to cAMP GO:0071320 IEP     cellular response to follicle-stimulating hormone stimulus GO:0071372 IEP     positive regulation of cell motility GO:2000147 ISO Subcellular Localization     extracellular region GO:0005576 IEA     extracellular region GO:0005576 ISO     basement membrane GO:0005604 IDA     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IDA     extracellular space GO:0005615 ISO     extracellular space GO:0005615 ISO     endosome GO:0005768 ISO     early endosome GO:0005769 IBA     early endosome GO:0005769 ISO     late endosome GO:0005770 ISO     endoplasmic reticulum membrane GO:0005789 IEA     plasma membrane GO:0005886 IBA     clathrin-coated pit GO:0005905 ISO     basal plasma membrane GO:0009925 ISO     cell surface GO:0009986 ISO     membrane GO:0016020 ISO     apical plasma membrane GO:0016324 ISO     vesicle coat GO:0030120 ISO     endocytic vesicle GO:0030139 ISO     dendrite GO:0030425 IDA     cytoplasmic vesicle GO:0031410 ISO     vesicle GO:0031982 ISO     basal part of cell GO:0045178 ISO     perinuclear region of cytoplasm GO:0048471 ISO     cell tip GO:0051286 IDA     recycling endosome GO:0055037 IBA     recycling endosome GO:0055037 ISO     dense body GO:0097433 ISO     HFE-transferrin receptor complex GO:1990712 ISO