Experiment description of studies that identified TMEM98 in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for TMEM98

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HTR6   Two-hybrid Homo sapiens 2 STX8 9482 Affinity Capture-MS Homo sapiens 3 STX7 8417 Affinity Capture-MS Homo sapiens 4 PTPRU   Affinity Capture-MS Homo sapiens 5 ERGIC2 51290 Affinity Capture-MS Homo sapiens 6 CD320 51293 Affinity Capture-MS Homo sapiens 7 VAMP3 9341 Affinity Capture-MS Homo sapiens 8 GMCL1   Affinity Capture-MS Homo sapiens 9 BMPR1A 657 Affinity Capture-MS Homo sapiens 10 CKM   Affinity Capture-MS Homo sapiens 11 VAMP8 8673 Affinity Capture-MS Homo sapiens 12 STX6 10228 Affinity Capture-MS Homo sapiens 13 RABEPK   Two-hybrid Homo sapiens 14 TNNT1   Two-hybrid Homo sapiens View the network

Pathways in which TMEM98 is involved

No pathways found