Gene description for KIF26A
Gene name kinesin family member 26A
Gene symbol KIF26A
Other names/aliases -
Species Homo sapiens
 Database cross references - KIF26A
ExoCarta ExoCarta_26153
Vesiclepedia VP_26153
Entrez Gene 26153
HGNC 20226
MIM 613231
UniProt Q9ULI4  
 KIF26A identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for KIF26A
Molecular Function
    microtubule motor activity GO:0003777 ISS
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    microtubule binding GO:0008017 ISS
    ATP hydrolysis activity GO:0016887 ISS
Biological Process
    regulation of cell growth by extracellular stimulus GO:0001560 ISS
    microtubule-based movement GO:0007018 ISS
    negative regulation of signal transduction GO:0009968 ISS
    regulation of neuron projection development GO:0010975 IMP
    cerebral cortex development GO:0021987 IMP
    enteric nervous system development GO:0048484 ISS
    regulation of neuron migration GO:2001222 IMP
Subcellular Localization
    cytosol GO:0005829 TAS
    microtubule GO:0005874 IEA
 Experiment description of studies that identified KIF26A in sEVs
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for KIF26A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Slain2  
Affinity Capture-MS Mus musculus
2 MAPK10 5602
Two-hybrid Homo sapiens
3 Setd3  
Affinity Capture-MS Mus musculus
4 Clspn  
Affinity Capture-MS Mus musculus
5 ARRB1 408
Affinity Capture-MS Homo sapiens
6 PLCXD2  
Affinity Capture-MS Homo sapiens
7 Magoh  
Affinity Capture-MS Mus musculus
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