Gene description for COX2
Gene name cytochrome c oxidase II, mitochondrial
Gene symbol COX2
Other names/aliases COII
Species Rattus norvegicus
 Database cross references - COX2
ExoCarta ExoCarta_26198
Vesiclepedia VP_26198
Entrez Gene 26198
UniProt P00406  
 COX2 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for COX2
Molecular Function
    cytochrome-c oxidase activity GO:0004129 IBA
    cytochrome-c oxidase activity GO:0004129 ISO
    cytochrome-c oxidase activity GO:0004129 ISS
    copper ion binding GO:0005507 IEA
Biological Process
    response to hypoxia GO:0001666 IEP
    lactation GO:0007595 IEP
    ATP synthesis coupled electron transport GO:0042773 IBA
    positive regulation of vasoconstriction GO:0045907 ISO
    proton transmembrane transport GO:1902600 IEA
Subcellular Localization
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 ISO
    mitochondrial membrane GO:0031966 ISO
    respiratory chain complex IV GO:0045277 ISO
    respiratory chain complex IV GO:0045277 ISS
 Experiment description of studies that identified COX2 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for COX2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Sumo3  
Affinity Capture-MS Rattus norvegicus
2 Itm2b 290364
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml



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