Gene description for TNFRSF21
Gene name	tumor necrosis factor receptor superfamily, member 21
Gene symbol	TNFRSF21
Other names/aliases	BM-018 CD358 DR6
Species	Homo sapiens
Database cross references - TNFRSF21
ExoCarta	ExoCarta_27242
Vesiclepedia	VP_27242
Entrez Gene	27242
HGNC	13469
MIM	605732
UniProt	O75509
TNFRSF21 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for TNFRSF21

Molecular Function     protein binding GO:0005515 IPI Biological Process     B cell apoptotic process GO:0001783 ISS     adaptive immune response GO:0002250 IBA     adaptive immune response GO:0002250 ISS     apoptotic process GO:0006915 IMP     humoral immune response GO:0006959 IBA     humoral immune response GO:0006959 ISS     axonal fasciculation GO:0007413 IEA     negative regulation of B cell proliferation GO:0030889 IBA     negative regulation of B cell proliferation GO:0030889 ISS     negative regulation of myelination GO:0031642 IBA     negative regulation of myelination GO:0031642 IMP     negative regulation of interleukin-10 production GO:0032693 ISS     negative regulation of interleukin-13 production GO:0032696 ISS     negative regulation of interleukin-5 production GO:0032714 ISS     negative regulation of T cell proliferation GO:0042130 IBA     negative regulation of T cell proliferation GO:0042130 ISS     myelination GO:0042552 ISS     regulation of oligodendrocyte differentiation GO:0048713 ISS     T cell receptor signaling pathway GO:0050852 ISS     neuron apoptotic process GO:0051402 IBA     cellular response to tumor necrosis factor GO:0071356 IDA     oligodendrocyte apoptotic process GO:0097252 IBA     oligodendrocyte apoptotic process GO:0097252 ISS Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISS     plasma membrane GO:0005886 TAS