Gene description for Capn2
Gene name	calpain 2, (m/II) large subunit
Gene symbol	Capn2
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Capn2
ExoCarta	ExoCarta_29154
Vesiclepedia	VP_29154
Entrez Gene	29154
UniProt	Q07009
Capn2 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041

Gene ontology annotations for Capn2

Molecular Function     calcium-dependent cysteine-type endopeptidase activity GO:0004198 IDA     calcium-dependent cysteine-type endopeptidase activity GO:0004198 IDA     calcium-dependent cysteine-type endopeptidase activity GO:0004198 IEA     calcium-dependent cysteine-type endopeptidase activity GO:0004198 ISO     calcium ion binding GO:0005509 IDA     calcium ion binding GO:0005509 IEA     protein binding GO:0005515 IPI     cytoskeletal protein binding GO:0008092 IDA     peptidase activity GO:0008233 ISO     enzyme binding GO:0019899 IPI     protein-containing complex binding GO:0044877 IPI Biological Process     response to hypoxia GO:0001666 IEP     blastocyst development GO:0001824 ISO     proteolysis GO:0006508 IBA     proteolysis GO:0006508 IDA     proteolysis GO:0006508 IEA     proteolysis GO:0006508 ISO     proteolysis GO:0006508 TAS     myoblast fusion GO:0007520 ISO     female pregnancy GO:0007565 IEP     response to mechanical stimulus GO:0009612 IEP     positive regulation of cardiac muscle cell apoptotic process GO:0010666 IMP     protein autoprocessing GO:0016540 IDA     protein catabolic process GO:0030163 IDA     regulation of interleukin-6 production GO:0032675 IMP     cellular response to interferon-beta GO:0035458 IEP     response to hydrogen peroxide GO:0042542 IEP     behavioral response to pain GO:0048266 IDA     synaptic vesicle endocytosis GO:0048488 ISO     proteolysis involved in protein catabolic process GO:0051603 ISO     cellular response to lipopolysaccharide GO:0071222 IEP     cellular response to amino acid stimulus GO:0071230 IDA     cellular response to amino acid stimulus GO:0071230 ISO     protein catabolic process at postsynapse GO:0140249 ISO     positive regulation of myoblast fusion GO:1901741 IMP     positive regulation of phosphatidylcholine biosynthetic process GO:2001247 IMP Subcellular Localization     chromatin GO:0000785 ISO     nucleus GO:0005634 ISO     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 IEA     cytoplasm GO:0005737 ISO     lysosome GO:0005764 ISO     endoplasmic reticulum GO:0005783 ISO     Golgi apparatus GO:0005794 ISO     cytosol GO:0005829 ISO     cytosol GO:0005829 ISS     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 ISS     focal adhesion GO:0005925 IDA     external side of plasma membrane GO:0009897 IDA     dendrite GO:0030425 IDA     pseudopodium GO:0031143 ISO     cell projection GO:0042995 IDA     neuronal cell body GO:0043025 IDA     membrane raft GO:0045121 ISO     membrane raft GO:0045121 ISS     perinuclear endoplasmic reticulum GO:0097038 ISO     presynapse GO:0098793 IEA     postsynapse GO:0098794 ISO     calpain complex GO:0110158 ISO