Gene description for Syngr1
Gene name synaptogyrin 1
Gene symbol Syngr1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Syngr1
ExoCarta ExoCarta_29205
Vesiclepedia VP_29205
Entrez Gene 29205
UniProt Q62876  
 Syngr1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Syngr1
Biological Process
    protein targeting GO:0006605 IDA
    regulated exocytosis GO:0045055 IMP
    regulation of long-term neuronal synaptic plasticity GO:0048169 ISO
    regulation of short-term neuronal synaptic plasticity GO:0048172 ISO
    synaptic vesicle membrane organization GO:0048499 IMP
    modulation of chemical synaptic transmission GO:0050804 ISO
    cellular response to leukemia inhibitory factor GO:1990830 ISO
Subcellular Localization
    synaptic vesicle GO:0008021 IDA
    membrane GO:0016020 IEA
    synaptic vesicle membrane GO:0030672 EXP
    synaptic vesicle membrane GO:0030672 IBA
    synaptic vesicle membrane GO:0030672 IDA
    synaptic vesicle membrane GO:0030672 IDA
    neuromuscular junction GO:0031594 IBA
    melanosome GO:0042470 IEA
    terminal bouton GO:0043195 HDA
    Schaffer collateral - CA1 synapse GO:0098685 ISO
 Experiment description of studies that identified Syngr1 in sEVs
1
Experiment ID 97
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Syngr1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Itm2b 290364
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Syngr1 is involved
PathwayEvidenceSource
Immune System IEA Reactome
Innate Immune System IEA Reactome
Neutrophil degranulation IEA Reactome





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