Gene description for Prdx2
Gene name	peroxiredoxin 2
Gene symbol	Prdx2
Other names/aliases	Tdpx1
Species	Rattus norvegicus
Database cross references - Prdx2
ExoCarta	ExoCarta_29338
Vesiclepedia	VP_29338
Entrez Gene	29338
UniProt	P35704
Prdx2 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Prdx2

Molecular Function     peroxidase activity GO:0004601 IEA     thioredoxin peroxidase activity GO:0008379 IBA     thioredoxin peroxidase activity GO:0008379 IEA     thioredoxin peroxidase activity GO:0008379 ISO     antioxidant activity GO:0016209 ISO Biological Process     defense response to tumor cell GO:0002357 IEA     defense response to tumor cell GO:0002357 ISO     respiratory burst involved in inflammatory response GO:0002536 IEA     respiratory burst involved in inflammatory response GO:0002536 ISO     response to oxidative stress GO:0006979 IBA     response to oxidative stress GO:0006979 IMP     response to oxidative stress GO:0006979 ISO     regulation of hydrogen peroxide metabolic process GO:0010310 IEA     regulation of hydrogen peroxide metabolic process GO:0010310 ISO     removal of superoxide radicals GO:0019430 IBA     removal of superoxide radicals GO:0019430 IEA     removal of superoxide radicals GO:0019430 ISO     positive regulation of blood coagulation GO:0030194 IEA     positive regulation of blood coagulation GO:0030194 ISO     negative regulation of lipopolysaccharide-mediated signaling pathway GO:0031665 IEA     negative regulation of lipopolysaccharide-mediated signaling pathway GO:0031665 ISO     negative regulation of NF-kappaB transcription factor activity GO:0032088 ISO     response to lipopolysaccharide GO:0032496 IEA     response to lipopolysaccharide GO:0032496 ISO     cellular response to oxidative stress GO:0034599 ISO     T cell proliferation GO:0042098 IEA     T cell proliferation GO:0042098 ISO     hydrogen peroxide metabolic process GO:0042743 ISO     hydrogen peroxide catabolic process GO:0042744 IBA     hydrogen peroxide catabolic process GO:0042744 IEA     hydrogen peroxide catabolic process GO:0042744 ISO     regulation of apoptotic process GO:0042981 ISO     T cell homeostasis GO:0043029 IEA     T cell homeostasis GO:0043029 ISO     positive regulation of MAPK cascade GO:0043410 IEA     positive regulation of MAPK cascade GO:0043410 ISO     negative regulation of neuron apoptotic process GO:0043524 IMP     leukocyte activation GO:0045321 IBA     cell redox homeostasis GO:0045454 IBA     negative regulation of T cell differentiation GO:0045581 IEA     negative regulation of T cell differentiation GO:0045581 ISO     thymus development GO:0048538 IEA     thymus development GO:0048538 ISO     extrinsic apoptotic signaling pathway GO:0097191 IEA     extrinsic apoptotic signaling pathway GO:0097191 ISO     cellular oxidant detoxification GO:0098869 IEA     negative regulation of extrinsic apoptotic signaling pathway GO:2001237 ISO     negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 IEA     negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 ISO Subcellular Localization     cytoplasm GO:0005737 IEA     cytosol GO:0005829 IBA