Gene description for Dync1h1
Gene name	dynein cytoplasmic 1 heavy chain 1
Gene symbol	Dync1h1
Other names/aliases	Dnch1 Dnchc1
Species	Rattus norvegicus
Database cross references - Dync1h1
ExoCarta	ExoCarta_29489
Vesiclepedia	VP_29489
Entrez Gene	29489
UniProt	P38650
Dync1h1 identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Dync1h1

Molecular Function     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     minus-end-directed microtubule motor activity GO:0008569 IBA     minus-end-directed microtubule motor activity GO:0008569 IEA     minus-end-directed microtubule motor activity GO:0008569 ISO     ATP hydrolysis activity GO:0016887 IEA     dynein intermediate chain binding GO:0045505 IBA     dynein intermediate chain binding GO:0045505 IEA     dynein light intermediate chain binding GO:0051959 IBA     dynein light intermediate chain binding GO:0051959 IEA     dynein light intermediate chain binding GO:0051959 ISO Biological Process     microtubule-based movement GO:0007018 IEA     mitotic spindle organization GO:0007052 IBA     nuclear migration GO:0007097 IBA     spermatid development GO:0007286 IEP     retrograde axonal transport GO:0008090 IBA     cytoplasmic microtubule organization GO:0031122 IBA     positive regulation of intracellular transport GO:0032388 IEA     positive regulation of intracellular transport GO:0032388 ISO     positive regulation of intracellular transport GO:0032388 ISS     P-body assembly GO:0033962 IEA     P-body assembly GO:0033962 ISO     stress granule assembly GO:0034063 IEA     stress granule assembly GO:0034063 ISO     establishment of spindle localization GO:0051293 IEA     establishment of spindle localization GO:0051293 ISO     cell division GO:0051301 IEA     regulation of mitotic spindle organization GO:0060236 IEA     regulation of mitotic spindle organization GO:0060236 ISO     regulation of mitotic spindle organization GO:0060236 ISS     regulation of metaphase plate congression GO:0090235 IEA     regulation of metaphase plate congression GO:0090235 ISO     regulation of metaphase plate congression GO:0090235 ISS     positive regulation of cold-induced thermogenesis GO:0120162 ISO     positive regulation of cold-induced thermogenesis GO:0120162 ISS     cellular response to 3,3',5-triiodo-L-thyronine GO:1905243 IEP     positive regulation of spindle assembly GO:1905832 IEA     positive regulation of spindle assembly GO:1905832 ISO     positive regulation of spindle assembly GO:1905832 ISS     cellular response to nerve growth factor stimulus GO:1990090 IEP Subcellular Localization     manchette GO:0002177 IDA     nuclear envelope GO:0005635 IDA     cytoplasm GO:0005737 IEA     cytoplasm GO:0005737 ISO     centrosome GO:0005813 IEA     centrosome GO:0005813 ISO     cytoplasmic dynein complex GO:0005868 IBA     cytoplasmic dynein complex GO:0005868 IEA     cytoplasmic dynein complex GO:0005868 ISO     microtubule GO:0005874 IEA     microtubule GO:0005874 ISO     cytoplasmic microtubule GO:0005881 IBA     cell cortex GO:0005938 IBA     filopodium GO:0030175 IEA     filopodium GO:0030175 ISO     dynein complex GO:0030286 IEA     dynein complex GO:0030286 ISO     axon GO:0030424 IDA     neuronal cell body GO:0043025 IDA     axon cytoplasm GO:1904115 IEA