Gene description for Atp2b1
Gene name	ATPase, Ca++ transporting, plasma membrane 1
Gene symbol	Atp2b1
Other names/aliases	Pmca1a Pmca1b Pmca1c
Species	Rattus norvegicus
Database cross references - Atp2b1
ExoCarta	ExoCarta_29598
Vesiclepedia	VP_29598
Entrez Gene	29598
UniProt	P11505
Atp2b1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Atp2b1

Molecular Function     P-type calcium transporter activity GO:0005388 IBA     P-type calcium transporter activity GO:0005388 IC     P-type calcium transporter activity GO:0005388 IEA     P-type calcium transporter activity GO:0005388 TAS     calmodulin binding GO:0005516 IEA     ATP binding GO:0005524 IEA     calcium ion transmembrane transporter activity GO:0015085 ISO     ATP hydrolysis activity GO:0016887 IEA     ATP hydrolysis activity GO:0016887 ISO     ATP hydrolysis activity GO:0016887 ISS     PDZ domain binding GO:0030165 IPI     metal ion binding GO:0046872 IEA     molecular function inhibitor activity GO:0140678 ISO Biological Process     negative regulation of cytokine production GO:0001818 IEA     negative regulation of cytokine production GO:0001818 ISO     negative regulation of cytokine production GO:0001818 ISS     regulation of vascular associated smooth muscle contraction GO:0003056 IEA     regulation of vascular associated smooth muscle contraction GO:0003056 ISO     regulation of vascular associated smooth muscle contraction GO:0003056 ISS     neural retina development GO:0003407 IEP     intracellular calcium ion homeostasis GO:0006874 ISO     intracellular calcium ion homeostasis GO:0006874 ISS     regulation of blood pressure GO:0008217 IEA     regulation of blood pressure GO:0008217 ISO     regulation of blood pressure GO:0008217 ISS     positive regulation of bone mineralization GO:0030501 IEA     positive regulation of bone mineralization GO:0030501 ISO     positive regulation of bone mineralization GO:0030501 ISS     regulation of cytosolic calcium ion concentration GO:0051480 IBA     regulation of cytosolic calcium ion concentration GO:0051480 IEA     regulation of cytosolic calcium ion concentration GO:0051480 ISO     regulation of cytosolic calcium ion concentration GO:0051480 ISS     negative regulation of cytosolic calcium ion concentration GO:0051481 IEA     negative regulation of cytosolic calcium ion concentration GO:0051481 ISO     negative regulation of cytosolic calcium ion concentration GO:0051481 ISS     positive regulation of calcium ion transport GO:0051928 IEA     positive regulation of calcium ion transport GO:0051928 ISO     positive regulation of calcium ion transport GO:0051928 ISS     calcium ion transmembrane transport GO:0070588 IEA     cellular response to vitamin D GO:0071305 IEP     cellular response to corticosterone stimulus GO:0071386 IEP     regulation of cellular response to insulin stimulus GO:1900076 IEA     regulation of cellular response to insulin stimulus GO:1900076 ISO     regulation of cellular response to insulin stimulus GO:1900076 ISS     calcium ion export GO:1901660 IMP     calcium ion export across plasma membrane GO:1990034 IEA     calcium ion export across plasma membrane GO:1990034 ISO Subcellular Localization     immunological synapse GO:0001772 IEA     immunological synapse GO:0001772 ISO     immunological synapse GO:0001772 ISS     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 TAS     cytoplasmic side of plasma membrane GO:0009898 IDA     basolateral plasma membrane GO:0016323 IDA     basolateral plasma membrane GO:0016323 IEA     basolateral plasma membrane GO:0016323 ISO     apical plasma membrane GO:0016324 IDA     synaptic vesicle membrane GO:0030672 IEA     synaptic vesicle membrane GO:0030672 ISO     synaptic vesicle membrane GO:0030672 ISS     dendrite membrane GO:0032590 IDA     dendritic spine membrane GO:0032591 IDA     neuronal cell body membrane GO:0032809 IDA     presynaptic membrane GO:0042734 IEA     presynaptic membrane GO:0042734 ISO     presynaptic membrane GO:0042734 ISO     presynaptic membrane GO:0042734 ISS     intracellular membrane-bounded organelle GO:0043231 IBA     apical part of cell GO:0045177 IDA     presynaptic active zone membrane GO:0048787 EXP     presynaptic active zone membrane GO:0048787 IDA     photoreceptor ribbon synapse GO:0098684 IEA     photoreceptor ribbon synapse GO:0098684 ISO     glutamatergic synapse GO:0098978 EXP     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 IEA     glutamatergic synapse GO:0098978 ISO     GABA-ergic synapse GO:0098982 EXP     GABA-ergic synapse GO:0098982 IDA