Gene description for Atp5l
Gene name ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
Gene symbol Atp5l
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Atp5l
ExoCarta ExoCarta_300677
Vesiclepedia VP_300677
Entrez Gene 300677
UniProt Q6PDU7  
 Atp5l identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Atp5l
Molecular Function
    proton transmembrane transporter activity GO:0015078 IEA
    proton-transporting ATP synthase activity, rotational mechanism GO:0046933 IBA
    proton-transporting ATP synthase activity, rotational mechanism GO:0046933 ISO
Biological Process
    proton motive force-driven ATP synthesis GO:0015986 IBA
    proton motive force-driven ATP synthesis GO:0015986 IEA
    proton motive force-driven mitochondrial ATP synthesis GO:0042776 ISO
    proton transmembrane transport GO:1902600 IEA
Subcellular Localization
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 IEA
    mitochondrial membrane GO:0031966 IEA
    proton-transporting ATP synthase complex GO:0045259 IDA
    proton-transporting ATP synthase complex GO:0045259 ISO
    proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 IDA
    proton-transporting ATP synthase complex, coupling factor F(o) GO:0045263 IEA
 Experiment description of studies that identified Atp5l in sEVs
1
Experiment ID 94
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Atp5l
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Itm2b 290364
Affinity Capture-MS Rattus norvegicus
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