Gene description for ACADSB
Gene name acyl-CoA dehydrogenase, short/branched chain
Gene symbol ACADSB
Other names/aliases 2-MEBCAD
ACAD7
SBCAD
Species Homo sapiens
 Database cross references - ACADSB
ExoCarta ExoCarta_36
Vesiclepedia VP_36
Entrez Gene 36
HGNC 91
MIM 600301
UniProt P45954  
 ACADSB identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for ACADSB
Molecular Function
    short-chain 2-methyl fatty acyl-CoA dehydrogenase activity GO:0003853 IDA
    acyl-CoA dehydrogenase activity GO:0003995 IBA
    short-chain fatty acyl-CoA dehydrogenase activity GO:0016937 IDA
    identical protein binding GO:0042802 IDA
    flavin adenine dinucleotide binding GO:0050660 IEA
Biological Process
    isoleucine catabolic process GO:0006550 IEA
    isoleucine catabolic process GO:0006550 IMP
    fatty acid metabolic process GO:0006631 IDA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial matrix GO:0005759 TAS
 Experiment description of studies that identified ACADSB in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ACADSB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PRSS16 10279
Co-fractionation Homo sapiens
2 GOLGA4  
Affinity Capture-MS Homo sapiens
3 AK4 205
Co-fractionation Homo sapiens
4 ACAD8 27034
Co-fractionation Homo sapiens
5 CS 1431
Proximity Label-MS Homo sapiens
6 SNTG1  
Affinity Capture-MS Homo sapiens
7 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
8 TSFM 10102
Proximity Label-MS Homo sapiens
9 FAF2 23197
Affinity Capture-MS Homo sapiens
10 PXDN 7837
Affinity Capture-MS Homo sapiens
11 C9orf78 51759
Affinity Capture-MS Homo sapiens
12 YTHDF1 54915
Affinity Capture-MS Homo sapiens
13 SCPEP1 59342
Co-fractionation Homo sapiens
14 MFSD4  
Affinity Capture-MS Homo sapiens
15 PCSK1  
Affinity Capture-MS Homo sapiens
16 THOC2 57187
Affinity Capture-MS Homo sapiens
17 PDHA1 5160
Proximity Label-MS Homo sapiens
18 NR3C1 2908
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 EGFR 1956
Affinity Capture-MS Homo sapiens
20 BMPR1A 657
Affinity Capture-MS Homo sapiens
21 COX8A  
Proximity Label-MS Homo sapiens
22 AAR2 25980
Affinity Capture-MS Homo sapiens
23 TXNDC12 51060
Co-fractionation Homo sapiens
24 DRG1 4733
Proximity Label-MS Homo sapiens
25 C21orf33  
Proximity Label-MS Homo sapiens
26 KDSR 2531
Co-fractionation Homo sapiens
27 HSCB 150274
Proximity Label-MS Homo sapiens
28 CLPP 8192
Proximity Label-MS Homo sapiens
29 AARS2  
Proximity Label-MS Homo sapiens
30 ATP6V1A 523
Co-fractionation Homo sapiens
31 SAR1B 51128
Affinity Capture-MS Homo sapiens
32 SPRTN  
Affinity Capture-MS Homo sapiens
33 PARK2  
Affinity Capture-MS Homo sapiens
34 USP19 10869
Affinity Capture-MS Homo sapiens
35 C1QBP 708
Proximity Label-MS Homo sapiens
36 XRCC6 2547
Co-fractionation Homo sapiens
37 MB21D1  
Proximity Label-MS Homo sapiens
38 KRAS 3845
Synthetic Lethality Homo sapiens
39 ACTR1A 10121
Co-fractionation Homo sapiens
40 C9orf72  
Affinity Capture-MS Homo sapiens
41 LYPLA1 10434
Co-fractionation Homo sapiens
42 DRG2 1819
Proximity Label-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here