Gene description for LCAT
Gene name	lecithin-cholesterol acyltransferase
Gene symbol	LCAT
Other names/aliases	-
Species	Homo sapiens
Database cross references - LCAT
ExoCarta	ExoCarta_3931
Vesiclepedia	VP_3931
Entrez Gene	3931
HGNC	6522
MIM	606967
UniProt	P04180
LCAT identified in sEVs derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for LCAT

Molecular Function     1-alkyl-2-acetylglycerophosphocholine esterase activity GO:0003847 IDA     phosphatidylcholine-sterol O-acyltransferase activity GO:0004607 IBA     phosphatidylcholine-sterol O-acyltransferase activity GO:0004607 IDA     phosphatidylcholine-sterol O-acyltransferase activity GO:0004607 NAS     phosphatidylcholine-sterol O-acyltransferase activity GO:0004607 TAS     sterol ester esterase activity GO:0004771 IDA     protein binding GO:0005515 IPI     apolipoprotein A-I binding GO:0034186 IPI     platelet-activating factor acetyltransferase activity GO:0047179 IDA Biological Process     lipid metabolic process GO:0006629 IBA     phospholipid metabolic process GO:0006644 IDA     phosphatidylcholine biosynthetic process GO:0006656 IDA     phosphatidylcholine biosynthetic process GO:0006656 IMP     cholesterol metabolic process GO:0008203 IDA     cholesterol metabolic process GO:0008203 IDA     cholesterol transport GO:0030301 IDA     very-low-density lipoprotein particle remodeling GO:0034372 IDA     high-density lipoprotein particle remodeling GO:0034375 IDA     high-density lipoprotein particle remodeling GO:0034375 TAS     lipoprotein biosynthetic process GO:0042158 IEA     cholesterol homeostasis GO:0042632 IDA     reverse cholesterol transport GO:0043691 IDA     phosphatidylcholine metabolic process GO:0046470 IDA     regulation of high-density lipoprotein particle assembly GO:0090107 IEA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IDA     high-density lipoprotein particle GO:0034364 IDA     extracellular exosome GO:0070062 HDA