Gene description for RAB19
Gene name RAB19, member RAS oncogene family
Gene symbol RAB19
Other names/aliases RAB19B
Species Homo sapiens
 Database cross references - RAB19
ExoCarta ExoCarta_401409
Vesiclepedia VP_401409
Entrez Gene 401409
HGNC 19982
UniProt A4D1S5  
 RAB19 identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for RAB19
Molecular Function
    GTPase activity GO:0003924 IBA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IEA
Biological Process
    autophagosome assembly GO:0000045 IBA
    intracellular protein transport GO:0006886 IBA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    endomembrane system GO:0012505 IBA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified RAB19 in sEVs
1
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for RAB19
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RAB3B 5865
Proximity Label-MS Homo sapiens
2 TOMM40 10452
Co-fractionation Homo sapiens
3 KRTAP10-8  
Two-hybrid Homo sapiens
4 RAB33A 9363
Affinity Capture-MS Homo sapiens
5 VDAC1 7416
Co-fractionation Homo sapiens
6 VDAC3 7419
Co-fractionation Homo sapiens
7 RABIF  
Two-hybrid Homo sapiens
8 TOMM5  
Co-fractionation Homo sapiens
9 LSM11  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RAB19 is involved
PathwayEvidenceSource
Metabolism of proteins TAS Reactome
Post-translational protein modification TAS Reactome
RAB geranylgeranylation TAS Reactome





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