Gene description for NCAM2
Gene name neural cell adhesion molecule 2
Gene symbol NCAM2
Other names/aliases NCAM21
Species Homo sapiens
 Database cross references - NCAM2
ExoCarta ExoCarta_4685
Vesiclepedia VP_4685
Entrez Gene 4685
HGNC 7657
MIM 602040
UniProt O15394  
 NCAM2 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for NCAM2
Molecular Function
    identical protein binding GO:0042802 IPI
Biological Process
    neuron cell-cell adhesion GO:0007158 TAS
    axonal fasciculation GO:0007413 IEA
Subcellular Localization
    plasma membrane GO:0005886 IDA
    membrane GO:0016020 TAS
    nuclear body GO:0016604 IDA
    axon GO:0030424 IEA
    neuron projection GO:0043005 IBA
    synaptic membrane GO:0097060 IEA
 Experiment description of studies that identified NCAM2 in sEVs
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for NCAM2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ARHGAP39  
Affinity Capture-MS Homo sapiens
2 JMJD6 23210
Affinity Capture-MS Homo sapiens
3 QDPR 5860
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which NCAM2 is involved
No pathways found





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