Gene description for Uqcrq
Gene name ubiquinol-cytochrome c reductase, complex III subunit VII
Gene symbol Uqcrq
Other names/aliases Qpc
Species Rattus norvegicus
 Database cross references - Uqcrq
ExoCarta ExoCarta_497902
Vesiclepedia VP_497902
Entrez Gene 497902
UniProt Q7TQ16  
 Uqcrq identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Uqcrq
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 IBA
    biological_process GO:0008150 ND
    subthalamus development GO:0021539 ISO
    pons development GO:0021548 ISO
    cerebellar Purkinje cell layer development GO:0021680 ISO
    hippocampus development GO:0021766 ISO
    thalamus development GO:0021794 ISO
    hypothalamus development GO:0021854 ISO
    pyramidal neuron development GO:0021860 ISO
    midbrain development GO:0030901 ISO
Subcellular Localization
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 ISO
    respiratory chain complex III GO:0045275 IBA
 Experiment description of studies that identified Uqcrq in sEVs
1
Experiment ID 97
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Uqcrq
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Itm2b 290364
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml



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