Gene description for IL23A
Gene name	interleukin 23, alpha subunit p19
Gene symbol	IL23A
Other names/aliases	IL-23 IL-23A IL23P19 P19 SGRF
Species	Homo sapiens
Database cross references - IL23A
ExoCarta	ExoCarta_51561
Vesiclepedia	VP_51561
Entrez Gene	51561
HGNC	15488
MIM	605580
UniProt	Q9NPF7
IL23A identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for IL23A

Molecular Function     cytokine activity GO:0005125 IEA     protein binding GO:0005515 IPI     interleukin-23 receptor binding GO:0045519 IDA Biological Process     positive regulation of T cell mediated cytotoxicity GO:0001916 ISS     positive regulation of defense response to virus by host GO:0002230 IBA     positive regulation of defense response to virus by host GO:0002230 IDA     positive regulation of defense response to virus by host GO:0002230 ISS     positive regulation of T-helper 1 type immune response GO:0002827 IBA     positive regulation of T-helper 1 type immune response GO:0002827 IDA     positive regulation of T-helper 1 type immune response GO:0002827 ISS     positive regulation of T-helper 1 type immune response GO:0002827 NAS     positive regulation of T-helper 1 type immune response GO:0002827 TAS     inflammatory response GO:0006954 IEA     cell surface receptor signaling pathway via JAK-STAT GO:0007259 IDA     negative regulation of interleukin-10 production GO:0032693 IMP     positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725 IDA     positive regulation of type II interferon production GO:0032729 IDA     positive regulation of type II interferon production GO:0032729 TAS     positive regulation of interleukin-10 production GO:0032733 IDA     positive regulation of interleukin-10 production GO:0032733 TAS     positive regulation of interleukin-12 production GO:0032735 IDA     positive regulation of interleukin-17 production GO:0032740 IDA     positive regulation of tumor necrosis factor production GO:0032760 IMP     positive regulation of natural killer cell activation GO:0032816 IC     positive regulation of natural killer cell proliferation GO:0032819 IDA     positive regulation of tissue remodeling GO:0034105 IC     T cell proliferation GO:0042098 IEA     positive regulation of T cell proliferation GO:0042102 IBA     positive regulation of T cell proliferation GO:0042102 IDA     positive regulation of activated T cell proliferation GO:0042104 IDA     positive regulation of memory T cell differentiation GO:0043382 ISS     innate immune response GO:0045087 IEA     positive regulation of osteoclast differentiation GO:0045672 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IEA     tissue remodeling GO:0048771 IEA     positive regulation of inflammatory response GO:0050729 IC     defense response to Gram-negative bacterium GO:0050829 IDA     positive regulation of NK T cell activation GO:0051135 IC     positive regulation of NK T cell activation GO:0051135 IDA     positive regulation of NK T cell proliferation GO:0051142 IDA     defense response to virus GO:0051607 IEA     positive regulation of neutrophil chemotaxis GO:0090023 IEA     cell surface receptor signaling pathway via STAT GO:0097696 IDA     positive regulation of non-canonical NF-kappaB signal transduction GO:1901224 TAS     positive regulation of T-helper 17 type immune response GO:2000318 ISS     positive regulation of T-helper 17 cell lineage commitment GO:2000330 IBA     positive regulation of T-helper 17 cell lineage commitment GO:2000330 ISS Subcellular Localization     extracellular region GO:0005576 TAS     endoplasmic reticulum lumen GO:0005788 TAS     interleukin-23 complex GO:0070743 IBA     interleukin-23 complex GO:0070743 IDA