Experiment description of studies that identified MFSD6 in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for MFSD6

Protein Interactor ExoCarta ID Identification method PubMed Species 1 GJA8   Two-hybrid Homo sapiens 2 GJB2   Two-hybrid Homo sapiens 3 GPX8 493869 Two-hybrid Homo sapiens 4 SGPL1 8879 Two-hybrid Homo sapiens 5 SLC10A6   Two-hybrid Homo sapiens 6 SSMEM1   Two-hybrid Homo sapiens 7 STX12 23673 Two-hybrid Homo sapiens 8 SYNDIG1   Two-hybrid Homo sapiens 9 TMEM179B 374395 Two-hybrid Homo sapiens 10 SLC16A2   Two-hybrid Homo sapiens 11 SMIM1 388588 Two-hybrid Homo sapiens 12 ERGIC3 51614 Two-hybrid Homo sapiens 13 TMEM258   Two-hybrid Homo sapiens 14 EBP   Two-hybrid Homo sapiens 15 CD79A   Two-hybrid Homo sapiens 16 TMEM242   Two-hybrid Homo sapiens 17 PDCD1LG2 80380 Two-hybrid Homo sapiens 18 GPR152   Two-hybrid Homo sapiens 19 C19orf18 147685 Two-hybrid Homo sapiens 20 SLC39A2   Two-hybrid Homo sapiens 21 GPR42   Two-hybrid Homo sapiens 22 APOL3   Two-hybrid Homo sapiens 23 ADIPOQ 9370 Two-hybrid Homo sapiens 24 TMEM237 65062 Two-hybrid Homo sapiens 25 ALG8   Two-hybrid Homo sapiens 26 SLC10A1   Two-hybrid Homo sapiens 27 APH1A 51107 Two-hybrid Homo sapiens 28 LY6E   Two-hybrid Homo sapiens 29 AQP7   Two-hybrid Homo sapiens 30 NKG7   Two-hybrid Homo sapiens 31 TSPO2   Two-hybrid Homo sapiens 32 SELK   Two-hybrid Homo sapiens 33 KIAA1644   Two-hybrid Homo sapiens 34 KIAA1919   Two-hybrid Homo sapiens View the network

Pathways in which MFSD6 is involved

No pathways found