Gene description for Mpp6
Gene name
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
Gene symbol
Mpp6
Other names/aliases
P55t Pals2
Species
Mus musculus
Database cross references - Mpp6
ExoCarta
ExoCarta_56524
Vesiclepedia
VP_56524
Entrez Gene
56524
UniProt
Q9JLB0
Mpp6 identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Mpp6
Experiment description of studies that identified Mpp6 in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Mpp6
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Pip4k2b
Co-fractionation
Mus musculus
2
NET1
10276
Protein-peptide
Homo sapiens
3
Tmem173
Proximity Label-MS
Mus musculus
4
CEP128
Affinity Capture-MS
Homo sapiens
5
CORO2A
Affinity Capture-MS
Homo sapiens
6
RASIP1
Affinity Capture-MS
Homo sapiens
7
LIN7C
55327
Affinity Capture-MS
Homo sapiens
8
Fancd2
Affinity Capture-MS
Mus musculus
9
RBM10
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which Mpp6 is involved
No pathways found