Gene description for KIF17
Gene name kinesin family member 17
Gene symbol KIF17
Other names/aliases KIF17B
KIF3X
KLP-2
OSM-3
Species Homo sapiens
 Database cross references - KIF17
ExoCarta ExoCarta_57576
Vesiclepedia VP_57576
Entrez Gene 57576
HGNC 19167
MIM 605037
UniProt Q9P2E2  
 KIF17 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for KIF17
Molecular Function
    ATP binding GO:0005524 IEA
    microtubule binding GO:0008017 IBA
    plus-end-directed microtubule motor activity GO:0008574 IBA
    ATP hydrolysis activity GO:0016887 IBA
Biological Process
    protein transport GO:0015031 IEA
    vesicle-mediated transport GO:0016192 IEA
    cell projection organization GO:0030030 IBA
    anterograde dendritic transport of neurotransmitter receptor complex GO:0098971 IBA
Subcellular Localization
    photoreceptor outer segment GO:0001750 IEA
    photoreceptor inner segment GO:0001917 IEA
    cytoplasm GO:0005737 IBA
    microtubule organizing center GO:0005815 IBA
    cytosol GO:0005829 TAS
    kinesin complex GO:0005871 IBA
    microtubule GO:0005874 IBA
    cilium GO:0005929 IBA
    cilium GO:0005929 ISS
    cilium GO:0005929 TAS
    axoneme GO:0005930 IEA
    photoreceptor connecting cilium GO:0032391 IEA
    dendrite cytoplasm GO:0032839 IEA
    ciliary basal body GO:0036064 IEA
    neuron projection GO:0043005 IBA
    postsynapse GO:0098794 IEA
    periciliary membrane compartment GO:1990075 IEA
 Experiment description of studies that identified KIF17 in sEVs
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for KIF17
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDC42 998
Affinity Capture-MS Homo sapiens
2 MAP3K10  
Two-hybrid Homo sapiens
3 Cdk1 12534
Affinity Capture-MS Mus musculus
4 GFI1B  
Two-hybrid Homo sapiens
5 MAP3K11 4296
Two-hybrid Homo sapiens
6 Magoh  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



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