Gene description for PTPRCAP
Gene name protein tyrosine phosphatase, receptor type, C-associated protein
Gene symbol PTPRCAP
Other names/aliases CD45-AP
LPAP
Species Homo sapiens
 Database cross references - PTPRCAP
ExoCarta ExoCarta_5790
Vesiclepedia VP_5790
Entrez Gene 5790
HGNC 9667
MIM 601577
UniProt Q14761  
 PTPRCAP identified in sEVs derived from the following tissue/cell type
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Thymus 23844026    
 Gene ontology annotations for PTPRCAP
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    defense response GO:0006952 TAS
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified PTPRCAP in sEVs
1
Experiment ID 231
MISEV standards
Biophysical techniques
Alix|CD63|CD9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 232
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 233
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
4
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PTPRCAP
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FN1 2335
Affinity Capture-MS Homo sapiens
2 UFSP2 55325
Affinity Capture-MS Homo sapiens
3 MYO1C 4641
Affinity Capture-MS Homo sapiens
4 CMTM6 54918
Affinity Capture-MS Homo sapiens
5 STX5 6811
Affinity Capture-MS Homo sapiens
6 STX10 8677
Affinity Capture-MS Homo sapiens
7 DCDC2  
Two-hybrid Homo sapiens
8 OSBPL8 114882
Affinity Capture-MS Homo sapiens
9 EEF1A1 1915
Two-hybrid Homo sapiens
10 C1orf27 54953
Affinity Capture-MS Homo sapiens
11 TPM4 7171
Affinity Capture-MS Homo sapiens
12 PTPRC 5788
Reconstituted Complex Homo sapiens
13 PGRMC1 10857
Affinity Capture-MS Homo sapiens
14 GOSR1 9527
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PTPRCAP is involved
No pathways found





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