Gene description for BBS4
Gene name	Bardet-Biedl syndrome 4
Gene symbol	BBS4
Other names/aliases	-
Species	Homo sapiens
Database cross references - BBS4
ExoCarta	ExoCarta_585
Vesiclepedia	VP_585
Entrez Gene	585
HGNC	969
MIM	600374
UniProt	Q96RK4
BBS4 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for BBS4

Molecular Function     protein binding GO:0005515 IPI     protein-macromolecule adaptor activity GO:0030674 IMP     dynactin binding GO:0034452 IDA     alpha-tubulin binding GO:0043014 IDA     beta-tubulin binding GO:0048487 IDA     RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 IPI Biological Process     microtubule cytoskeleton organization GO:0000226 ISS     mitotic cytokinesis GO:0000281 IMP     neuron migration GO:0001764 IEA     B cell homeostasis GO:0001782 IEA     neural tube closure GO:0001843 ISS     retina homeostasis GO:0001895 ISS     negative regulation of systemic arterial blood pressure GO:0003085 IEA     centrosome cycle GO:0007098 IMP     spermatid development GO:0007286 ISS     visual perception GO:0007601 IEA     sensory perception of smell GO:0007608 ISS     gene expression GO:0010467 IEA     negative regulation of gene expression GO:0010629 IEA     protein transport GO:0015031 IEA     Wnt signaling pathway GO:0016055 IEA     dendrite development GO:0016358 ISS     regulation of lipid metabolic process GO:0019216 ISS     ventricular system development GO:0021591 IEA     striatum development GO:0021756 ISS     hippocampus development GO:0021766 ISS     cerebral cortex development GO:0021987 ISS     adult behavior GO:0030534 ISS     negative regulation of actin filament polymerization GO:0030837 IEA     regulation of cytokinesis GO:0032465 IMP     protein localization to organelle GO:0033365 ISS     erythrocyte homeostasis GO:0034101 IEA     microtubule anchoring at centrosome GO:0034454 IMP     social behavior GO:0035176 IEA     photoreceptor cell outer segment organization GO:0035845 IEA     negative regulation of appetite by leptin-mediated signaling pathway GO:0038108 ISS     positive regulation of multicellular organism growth GO:0040018 IEA     fat cell differentiation GO:0045444 ISS     photoreceptor cell maintenance GO:0045494 ISS     positive regulation of cilium assembly GO:0045724 ISS     retinal rod cell development GO:0046548 ISS     brain morphogenesis GO:0048854 ISS     sensory processing GO:0050893 TAS     maintenance of protein location in nucleus GO:0051457 IGI     regulation of stress fiber assembly GO:0051492 IEA     cilium assembly GO:0060271 IBA     cilium assembly GO:0060271 ISS     cilium assembly GO:0060271 NAS     regulation of cilium beat frequency involved in ciliary motility GO:0060296 ISS     face development GO:0060324 IEA     fat pad development GO:0060613 IEA     protein localization to cilium GO:0061512 IBA     protein localization to cilium GO:0061512 IMP     protein localization to centrosome GO:0071539 IMP     sperm flagellum assembly GO:0120316 IEA     regulation of non-motile cilium assembly GO:1902855 IEA     protein localization to photoreceptor outer segment GO:1903546 IEA     non-motile cilium assembly GO:1905515 ISS Subcellular Localization     pericentriolar material GO:0000242 IDA     photoreceptor outer segment GO:0001750 IEA     photoreceptor inner segment GO:0001917 IEA     nucleus GO:0005634 IEA     centrosome GO:0005813 IDA     centriole GO:0005814 IDA     cytosol GO:0005829 TAS     cilium GO:0005929 IDA     motile cilium GO:0031514 IDA     photoreceptor connecting cilium GO:0032391 IEA     centriolar satellite GO:0034451 IDA     BBSome GO:0034464 IDA     BBSome GO:0034464 IPI     ciliary transition zone GO:0035869 IDA     ciliary basal body GO:0036064 IBA     ciliary basal body GO:0036064 IDA     ciliary membrane GO:0060170 IDA     non-motile cilium GO:0097730 IDA