Gene description for Nsf
Gene name	N-ethylmaleimide-sensitive factor
Gene symbol	Nsf
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Nsf
ExoCarta	ExoCarta_60355
Vesiclepedia	VP_60355
Entrez Gene	60355
UniProt	Q9QUL6
Nsf identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Nsf

Molecular Function     SNARE binding GO:0000149 ISS     DNA clamp loader activity GO:0003689 IEA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     ATP hydrolysis activity GO:0016887 IBA     ATP hydrolysis activity GO:0016887 IDA     ATP hydrolysis activity GO:0016887 IEA     ATP hydrolysis activity GO:0016887 ISO     syntaxin-1 binding GO:0017075 IEA     syntaxin-1 binding GO:0017075 ISO     protein kinase binding GO:0019901 IEA     protein kinase binding GO:0019901 ISO     syntaxin binding GO:0019905 ISO     PDZ domain binding GO:0030165 IEA     PDZ domain binding GO:0030165 ISO     small GTPase binding GO:0031267 IPI     D1 dopamine receptor binding GO:0031748 IPI     ionotropic glutamate receptor binding GO:0035255 IEA     ionotropic glutamate receptor binding GO:0035255 IPI     ionotropic glutamate receptor binding GO:0035255 ISO     ATP-dependent protein binding GO:0043008 IPI     protein-containing complex binding GO:0044877 IDA     protein-containing complex binding GO:0044877 IEA     protein-containing complex binding GO:0044877 ISO     protein-containing complex binding GO:0044877 ISS     metal ion binding GO:0046872 IEA     cohesin loader activity GO:0061775 IEA     protein serine/threonine kinase binding GO:0120283 IPI     ATP-dependent protein disaggregase activity GO:0140545 ISS     chromatin extrusion motor activity GO:0140584 IEA     ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA     ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA Biological Process     positive regulation of receptor recycling GO:0001921 IEA     positive regulation of receptor recycling GO:0001921 ISO     regulation of receptor internalization GO:0002090 IDA     chromatin remodeling GO:0006338 IEA     potassium ion transport GO:0006813 IEA     potassium ion transport GO:0006813 ISO     intracellular protein transport GO:0006886 IEA     intracellular protein transport GO:0006886 ISO     intra-Golgi vesicle-mediated transport GO:0006891 IBA     protein transport GO:0015031 IEA     vesicle-mediated transport GO:0016192 IMP     regulation of exocytosis GO:0017157 IMP     protein-containing complex disassembly GO:0032984 IDA     SNARE complex disassembly GO:0035494 IEA     SNARE complex disassembly GO:0035494 ISS     Golgi to plasma membrane protein transport GO:0043001 IBA     positive regulation of protein catabolic process GO:0045732 IEA     positive regulation of protein catabolic process GO:0045732 ISO     positive regulation of receptor-mediated endocytosis GO:0048260 IMP     chromatin looping GO:0140588 IEA Subcellular Localization     cytoplasm GO:0005737 IEA     Golgi apparatus GO:0005794 IEA     Golgi apparatus GO:0005794 ISO     Golgi stack GO:0005795 IBA     Golgi stack GO:0005795 IDA     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     postsynaptic density GO:0014069 TAS     dendritic shaft GO:0043198 IDA     GABA-ergic synapse GO:0098982 IDA     postsynaptic specialization, intracellular component GO:0099091 IDA