Gene description for SAA2
Gene name serum amyloid A2
Gene symbol SAA2
Other names/aliases -
Species Homo sapiens
 Database cross references - SAA2
ExoCarta ExoCarta_6289
Vesiclepedia VP_6289
Entrez Gene 6289
HGNC 10514
MIM 104751
UniProt P0DJI9  
 SAA2 identified in sEVs derived from the following tissue/cell type
Prostate cancer cells 22723089    
Saliva 19199708    
 Gene ontology annotations for SAA2
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    acute-phase response GO:0006953 IEA
Subcellular Localization
    high-density lipoprotein particle GO:0034364 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified SAA2 in sEVs
1
Experiment ID 146
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|CD9
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name RWPE - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
2
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for SAA2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APOD 347
Cross-Linking-MS (XL-MS) Homo sapiens
2 APOB 338
Cross-Linking-MS (XL-MS) Homo sapiens
3 SAA1 6288
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
4 TIMM10  
Affinity Capture-MS Homo sapiens
5 CIDEB  
Two-hybrid Homo sapiens
6 EGFR 1956
Negative Genetic Homo sapiens
7 APOA2 336
Cross-Linking-MS (XL-MS) Homo sapiens
8 CLU 1191
Cross-Linking-MS (XL-MS) Homo sapiens
9 UBE2U  
Affinity Capture-MS Homo sapiens
10 APOA1 335
Two-hybrid Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml
 Pathways in which SAA2 is involved
No pathways found





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