Experiment description of studies that identified FBRS in sEVs

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for FBRS

Protein Interactor ExoCarta ID Identification method PubMed Species 1 KDF1   Affinity Capture-MS Homo sapiens 2 GATA1   Proximity Label-MS Homo sapiens 3 SOX7   Proximity Label-MS Homo sapiens 4 TLX1   Proximity Label-MS Homo sapiens 5 KDM2B 84678 Affinity Capture-MS Homo sapiens 6 RING1 6015 Affinity Capture-MS Homo sapiens 7 CBX2   Affinity Capture-MS Homo sapiens 8 TLX2   Proximity Label-MS Homo sapiens 9 TLX3   Proximity Label-MS Homo sapiens 10 PCGF5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 CSNK2B 1460 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 YAF2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 MBLAC2 153364 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 L3MBTL2   Affinity Capture-MS Homo sapiens 15 HELZ 9931 Affinity Capture-MS Homo sapiens 16 NFIB   Proximity Label-MS Homo sapiens 17 PGK1 5230 Affinity Capture-MS Homo sapiens 18 XPO1 7514 Affinity Capture-MS Homo sapiens 19 RPL30 6156 Affinity Capture-MS Homo sapiens 20 CBX8 57332 Affinity Capture-MS Homo sapiens 21 WWOX 51741 Affinity Capture-MS Homo sapiens 22 MGA   Affinity Capture-MS Homo sapiens 23 SKP1 6500 Affinity Capture-MS Homo sapiens 24 SOX6   Proximity Label-MS Homo sapiens 25 UBE2E3 10477 Affinity Capture-MS Homo sapiens 26 GATA2   Proximity Label-MS Homo sapiens 27 KLF3   Proximity Label-MS Homo sapiens 28 FOXI1   Proximity Label-MS Homo sapiens 29 Cbx7   Affinity Capture-MS Mus musculus 30 NR3C1 2908 Proximity Label-MS Homo sapiens 31 SOX17   Proximity Label-MS Homo sapiens 32 CSNK2A1 1457 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 FANCD2OS   Affinity Capture-MS Homo sapiens 34 CTBP1 1487 Proximity Label-MS Homo sapiens 35 PHC3   Affinity Capture-MS Homo sapiens 36 PAX9   Proximity Label-MS Homo sapiens 37 TAF1   Affinity Capture-MS Homo sapiens 38 PCGF3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 TNRC6B   Affinity Capture-MS Homo sapiens 40 PRPF31 26121 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 41 BCOR   Affinity Capture-MS Homo sapiens 42 KIAA0430   Affinity Capture-MS Homo sapiens 43 PAX6   Proximity Label-MS Homo sapiens 44 PCGF2 7703 Affinity Capture-MS Homo sapiens 45 E2F6 1876 Affinity Capture-MS Homo sapiens 46 CBX3 11335 Affinity Capture-MS Homo sapiens 47 Ring1   Affinity Capture-MS Mus musculus 48 PAX7   Proximity Label-MS Homo sapiens 49 AGBL5   Affinity Capture-MS Homo sapiens 50 ERG   Proximity Label-MS Homo sapiens 51 CBX4   Affinity Capture-MS Homo sapiens 52 Uso1 56041 Affinity Capture-MS Mus musculus 53 KLF8   Proximity Label-MS Homo sapiens 54 PCGF6   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 55 DCAF7 10238 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens 56 CSNK2A2 1459 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 PHC1   Affinity Capture-MS Homo sapiens 58 NUP35 129401 Proximity Label-MS Homo sapiens 59 TBR1   Proximity Label-MS Homo sapiens 60 SIRT6   Affinity Capture-MS Homo sapiens 61 CBX6   Affinity Capture-MS Homo sapiens 62 KCTD17 79734 Affinity Capture-MS Homo sapiens 63 PCGF1 84759 Affinity Capture-MS Homo sapiens 64 SCMH1   Affinity Capture-MS Homo sapiens 65 RNF2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 66 SOWAHA   Affinity Capture-MS Homo sapiens 67 AR 367 Proximity Label-MS Homo sapiens 68 PHC2   Affinity Capture-MS Homo sapiens 69 P4HA3 283208 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 70 KLF15   Proximity Label-MS Homo sapiens 71 T   Proximity Label-MS Homo sapiens 72 KRTAP13-2   Affinity Capture-MS Homo sapiens 73 AUTS2   Affinity Capture-MS Homo sapiens 74 IRF4   Proximity Label-MS Homo sapiens 75 MYCL   Affinity Capture-MS Homo sapiens 76 NFIC 4782 Proximity Label-MS Homo sapiens 77 RYBP   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 78 BCORL1   Affinity Capture-MS Homo sapiens 79 SOX2   Proximity Label-MS Homo sapiens 80 BMI1   Affinity Capture-MS Homo sapiens 81 SP7   Proximity Label-MS Homo sapiens 82 FEV   Proximity Label-MS Homo sapiens View the network

Pathways in which FBRS is involved

No pathways found