Gene description for Rab5a
Gene name	RAB5A, member RAS oncogene family
Gene symbol	Rab5a
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Rab5a
ExoCarta	ExoCarta_64633
Vesiclepedia	VP_64633
Entrez Gene	64633
UniProt	M0RC99
Rab5a identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Rab5a

Molecular Function     GTPase activity GO:0003924 IBA     GTPase activity GO:0003924 IEA     GTPase activity GO:0003924 ISO     G protein activity GO:0003925 IEA     GTP binding GO:0005525 IEA     GTP binding GO:0005525 ISO     guanyl nucleotide binding GO:0019001 ISO     GDP binding GO:0019003 ISO     GDP-dissociation inhibitor binding GO:0051021 IDA     membrane scission GTPase motor activity GO:1990606 IEA Biological Process     intracellular protein transport GO:0006886 IBA     endocytosis GO:0006897 IBA     endocytosis GO:0006897 IMP     endocytosis GO:0006897 ISO     endocytosis GO:0006897 ISO     phagocytosis GO:0006909 IEA     endosome organization GO:0007032 IMP     positive regulation of smooth muscle cell migration GO:0014911 IMP     protein transport GO:0015031 IEA     vesicle-mediated transport GO:0016192 NAS     receptor internalization GO:0031623 ISO     synaptic vesicle recycling GO:0036465 ISO     early endosome to late endosome transport GO:0045022 ISO     positive regulation of exocytosis GO:0045921 ISO     regulation of long-term neuronal synaptic plasticity GO:0048169 IBA     regulation of long-term neuronal synaptic plasticity GO:0048169 IMP     synaptic vesicle endocytosis GO:0048488 IDA     synaptic vesicle endocytosis GO:0048488 IMP     positive regulation of smooth muscle cell proliferation GO:0048661 IMP     regulation of endosome size GO:0051036 ISO     regulation of filopodium assembly GO:0051489 ISO     canonical Wnt signaling pathway GO:0060070 ISO     postsynaptic neurotransmitter receptor internalization GO:0098884 IDA     postsynaptic neurotransmitter receptor internalization GO:0098884 IMP     amyloid-beta clearance by transcytosis GO:0150093 ISO     regulation of synaptic vesicle exocytosis GO:2000300 ISO     regulation of synaptic vesicle exocytosis GO:2000300 ISS Subcellular Localization     ruffle GO:0001726 ISO     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 ISO     endosome GO:0005768 IDA     endosome GO:0005768 ISO     early endosome GO:0005769 IDA     early endosome GO:0005769 IEA     early endosome GO:0005769 ISO     lipid droplet GO:0005811 ISO     cytosol GO:0005829 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     synaptic vesicle GO:0008021 IDA     endosome membrane GO:0010008 ISO     endomembrane system GO:0012505 IBA     actin cytoskeleton GO:0015629 ISO     endocytic vesicle GO:0030139 IBA     endocytic vesicle GO:0030139 ISO     axon GO:0030424 IBA     axon GO:0030424 IDA     dendrite GO:0030425 IBA     dendrite GO:0030425 IDA     phagocytic vesicle membrane GO:0030670 IEA     synaptic vesicle membrane GO:0030672 EXP     synaptic vesicle membrane GO:0030672 IBA     synaptic vesicle membrane GO:0030672 IDA     synaptic vesicle membrane GO:0030672 IDA     synaptic vesicle membrane GO:0030672 IMP     early endosome membrane GO:0031901 IEA     early phagosome GO:0032009 ISO     early phagosome GO:0032009 ISS     protein-containing complex GO:0032991 IDA     somatodendritic compartment GO:0036477 IDA     somatodendritic compartment GO:0036477 ISO     melanosome GO:0042470 IEA     zymogen granule membrane GO:0042589 IDA     neuronal cell body GO:0043025 IDA     terminal bouton GO:0043195 HDA     terminal bouton GO:0043195 ISO     terminal bouton GO:0043195 ISS     intracellular membrane-bounded organelle GO:0043231 ISO     axon terminus GO:0043679 IDA     membrane raft GO:0045121 ISO     phagocytic vesicle GO:0045335 ISO     phagocytic vesicle GO:0045335 ISS     perinuclear region of cytoplasm GO:0048471 IDA     recycling endosome GO:0055037 IDA     exocytic vesicle GO:0070382 ISO     sorting endosome GO:0097443 ISO     cytoplasmic side of early endosome membrane GO:0098559 ISO     presynaptic endosome GO:0098830 IDA     presynaptic endosome GO:0098830 IMP     postsynaptic early endosome GO:0098842 IBA     postsynaptic endocytic zone membrane GO:0098844 IDA     postsynaptic endocytic zone membrane GO:0098844 IMP     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 IMP