Gene description for Rab13
Gene name RAB13, member RAS oncogene family
Gene symbol Rab13
Other names/aliases 0610007N03Rik
B230212B15Rik
Species Mus musculus
 Database cross references - Rab13
ExoCarta ExoCarta_68328
Vesiclepedia VP_68328
Entrez Gene 68328
UniProt Q9DD03  
 Rab13 identified in sEVs derived from the following tissue/cell type
Embryonic fibroblasts 18494037    
 Gene ontology annotations for Rab13
Molecular Function
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 ISO
    GTPase activity GO:0003924 TAS
    GTP binding GO:0005525 ISO
    GTP binding GO:0005525 ISS
    protein kinase A catalytic subunit binding GO:0034236 ISO
Biological Process
    intracellular protein transport GO:0006886 TAS
    exocytosis GO:0006887 IBA
    Golgi to plasma membrane transport GO:0006893 IEA
    Golgi to plasma membrane transport GO:0006893 ISO
    protein kinase A signaling GO:0010737 IBA
    protein kinase A signaling GO:0010737 ISO
    protein kinase A signaling GO:0010737 ISS
    endosomal transport GO:0016197 ISO
    endosomal transport GO:0016197 ISS
    cortical actin cytoskeleton organization GO:0030866 ISO
    cortical actin cytoskeleton organization GO:0030866 ISS
    neuron projection development GO:0031175 ISO
    neuron projection development GO:0031175 ISS
    endocytic recycling GO:0032456 IBA
    endocytic recycling GO:0032456 IMP
    endocytic recycling GO:0032456 ISO
    cellular response to insulin stimulus GO:0032869 ISO
    cellular response to insulin stimulus GO:0032869 ISS
    endothelial cell chemotaxis GO:0035767 IMP
    trans-Golgi network to recycling endosome transport GO:0044795 ISS
    bicellular tight junction assembly GO:0070830 ISO
    bicellular tight junction assembly GO:0070830 ISS
    protein localization to plasma membrane GO:0072659 ISO
    protein localization to plasma membrane GO:0072659 ISS
    establishment of Sertoli cell barrier GO:0097368 ISO
    establishment of Sertoli cell barrier GO:0097368 ISS
    protein localization to cell leading edge GO:1902463 IMP
Subcellular Localization
    endosome GO:0005768 IBA
    Golgi apparatus GO:0005794 IDA
    trans-Golgi network GO:0005802 ISO
    trans-Golgi network GO:0005802 ISS
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 ISO
    plasma membrane GO:0005886 ISS
    cell-cell junction GO:0005911 IDA
    bicellular tight junction GO:0005923 IDA
    bicellular tight junction GO:0005923 ISO
    synaptic vesicle GO:0008021 IBA
    lateral plasma membrane GO:0016328 ISO
    lateral plasma membrane GO:0016328 ISS
    extrinsic component of plasma membrane GO:0019897 TAS
    lamellipodium GO:0030027 IDA
    endocytic vesicle GO:0030139 IDA
    endocytic vesicle GO:0030139 ISO
    trans-Golgi network transport vesicle GO:0030140 IBA
    cytoplasmic vesicle membrane GO:0030659 TAS
    cytoplasmic vesicle GO:0031410 ISO
    cytoplasmic vesicle GO:0031410 ISS
    cytoplasmic vesicle GO:0031410 TAS
    insulin-responsive compartment GO:0032593 ISO
    insulin-responsive compartment GO:0032593 ISS
    neuron projection GO:0043005 ISO
    neuron projection GO:0043005 ISS
    recycling endosome GO:0055037 ISO
    recycling endosome GO:0055037 ISS
    recycling endosome membrane GO:0055038 IEA
 Experiment description of studies that identified Rab13 in sEVs
1
Experiment ID 73
MISEV standards
EM
Biophysical techniques
HSP70|HSP90
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 18494037    
Organism Mus musculus
Experiment description Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes.
Authors "Ji H, Erfani N, Tauro BJ, Kapp EA, Zhu HJ, Moritz RL, Lim JW, Simpson RJ"
Journal name ELEC
Publication year 2008
Sample Embryonic fibroblasts
Sample name NIH3T3
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA]
Western blotting
 Protein-protein interactions for Rab13
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Micall2  
Two-hybrid Mus musculus
Affinity Capture-Western Mus musculus
Co-localization Mus musculus
2 TGFBR1 7046
Affinity Capture-Luminescence Homo sapiens
3 SMURF2 64750
Affinity Capture-Luminescence Homo sapiens
4 SMAD4  
Affinity Capture-Luminescence Homo sapiens
5 Atg5  
Affinity Capture-MS Mus musculus
6 Fancd2  
Affinity Capture-MS Mus musculus
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