Gene description for ELMO3
Gene name engulfment and cell motility 3
Gene symbol ELMO3
Other names/aliases CED-12
CED12
ELMO-3
Species Homo sapiens
 Database cross references - ELMO3
ExoCarta ExoCarta_79767
Vesiclepedia VP_79767
Entrez Gene 79767
HGNC 17289
MIM 606422
UniProt Q96BJ8  
 ELMO3 identified in sEVs derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for ELMO3
Molecular Function
    protein binding GO:0005515 IPI
    SH3 domain binding GO:0017124 IEA
Biological Process
    phagocytosis GO:0006909 IEA
    apoptotic process GO:0006915 IEA
    actin filament organization GO:0007015 IBA
    cell motility GO:0048870 IBA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified ELMO3 in sEVs
1
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ELMO3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Smchd1  
Affinity Capture-MS Mus musculus
2 SDC2 6383
Affinity Capture-MS Homo sapiens
3 Cry1  
Affinity Capture-MS Mus musculus
4 Ptpn2  
Affinity Capture-MS Mus musculus
5 LLGL2 3993
Affinity Capture-MS Homo sapiens
6 UBE2S  
Affinity Capture-MS Homo sapiens
7 DOCK4 9732
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 Cyr61  
Affinity Capture-MS Mus musculus
9 FOXP2 93986
Affinity Capture-MS Homo sapiens
10 ELMO2 63916
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 KIF15 56992
Affinity Capture-MS Homo sapiens
12 ELMO1 9844
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 HSPA8 3312
Affinity Capture-MS Homo sapiens
14 DOCK5 80005
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 UBR4 23352
Affinity Capture-MS Homo sapiens
16 TUSC2  
Affinity Capture-MS Homo sapiens
17 KCMF1 56888
Affinity Capture-MS Homo sapiens
18 SYMPK 8189
Affinity Capture-MS Homo sapiens
19 Rabep2  
Affinity Capture-MS Mus musculus
20 HAUS5 23354
Affinity Capture-MS Homo sapiens
21 METTL21B  
Affinity Capture-MS Homo sapiens
22 RBM7  
Affinity Capture-MS Homo sapiens
23 TUBA1A 7846
Affinity Capture-MS Homo sapiens
24 PCNA 5111
Affinity Capture-MS Homo sapiens
25 ARL4A  
Affinity Capture-Western Homo sapiens
26 Mis12  
Affinity Capture-MS Mus musculus
27 LOC100506753  
Protein-RNA Homo sapiens
28 DOCK1 1793
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
30 FAM174A 345757
Affinity Capture-MS Homo sapiens
31 CD244 51744
Affinity Capture-MS Homo sapiens
32 RAC2 5880
Affinity Capture-MS Homo sapiens
33 CAB39L 81617
Affinity Capture-MS Homo sapiens
34 VPS18 57617
Affinity Capture-MS Homo sapiens
35 SLC33A1 9197
Affinity Capture-MS Homo sapiens
36 DOCK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ELMO3 is involved
No pathways found





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