Gene description for TRABD
Gene name TraB domain containing
Gene symbol TRABD
Other names/aliases LP6054
PP2447
Species Homo sapiens
 Database cross references - TRABD
ExoCarta ExoCarta_80305
Vesiclepedia VP_80305
Entrez Gene 80305
HGNC 28805
UniProt Q9H4I3  
 TRABD identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for TRABD
Molecular Function
    mitochondrion-mitochondrion outer membrane tether activity GO:0160204 IMP
Biological Process
    mitochondrial fusion GO:0008053 IMP
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrial outer membrane GO:0005741 IDA
 Experiment description of studies that identified TRABD in sEVs
1
Experiment ID 234
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for TRABD
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HIPK4  
Affinity Capture-MS Homo sapiens
2 TOMM40 10452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 FBXL4 26235
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 NME2 4831
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 MAVS 57506
Proximity Label-MS Homo sapiens
6 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
7 DNAJC11 55735
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 MTCH1 23787
Proximity Label-MS Homo sapiens
9 LAMTOR1 55004
Proximity Label-MS Homo sapiens
10 UQCRQ 27089
Affinity Capture-MS Homo sapiens
11 SLC25A12 8604
Proximity Label-MS Homo sapiens
12 TRAK1 22906
Affinity Capture-MS Homo sapiens
13 TMPRSS5  
Affinity Capture-MS Homo sapiens
14 HSPA6 3310
Affinity Capture-MS Homo sapiens
15 JMJD4  
Affinity Capture-MS Homo sapiens
16 FCN1 2219
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 HSPA8 3312
Affinity Capture-MS Homo sapiens
18 SLC25A51  
Proximity Label-MS Homo sapiens
19 MTX2 10651
Proximity Label-MS Homo sapiens
20 RPA2 6118
Proximity Label-MS Homo sapiens
21 PON2 5445
Affinity Capture-MS Homo sapiens
22 TPTE  
Affinity Capture-MS Homo sapiens
23 FAM96A  
Affinity Capture-MS Homo sapiens
24 MTCH2 23788
Proximity Label-MS Homo sapiens
25 ATP12A 479
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 SLC1A5 6510
Affinity Capture-MS Homo sapiens
27 CUL3 8452
Affinity Capture-MS Homo sapiens
28 SAMM50 25813
Proximity Label-MS Homo sapiens
29 UBC 7316
Affinity Capture-MS Homo sapiens
30 OCIAD1 54940
Proximity Label-MS Homo sapiens
31 RNF40 9810
Affinity Capture-MS Homo sapiens
32 HGSNAT 138050
Affinity Capture-MS Homo sapiens
33 PPTC7 160760
Affinity Capture-MS Homo sapiens
34 HSP90AA4P 3323
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 FIS1 51024
Proximity Label-MS Homo sapiens
36 MEI1  
Affinity Capture-MS Homo sapiens
37 BECN1 8678
Affinity Capture-MS Homo sapiens
38 RPA3 6119
Proximity Label-MS Homo sapiens
39 DNAJC5B  
Proximity Label-MS Homo sapiens
40 RAB7A 7879
Proximity Label-MS Homo sapiens
41 ATP2B2 491
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 D2HGDH 728294
Affinity Capture-MS Homo sapiens
43 OPA1 4976
Proximity Label-MS Homo sapiens
44 HSDL1 83693
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 BRD1 23774
Affinity Capture-MS Homo sapiens
46 SERBP1 26135
Affinity Capture-MS Homo sapiens
47 ILK 3611
Affinity Capture-MS Homo sapiens
48 NT5DC1 221294
Affinity Capture-MS Homo sapiens
49 HAX1  
Proximity Label-MS Homo sapiens
50 AKR7A3 22977
Affinity Capture-MS Homo sapiens
51 MARCH5  
Proximity Label-MS Homo sapiens
52 PLD6  
Affinity Capture-MS Homo sapiens
53 RHOT2 89941
Proximity Label-MS Homo sapiens
54 AKAP1 8165
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 ASB14  
Affinity Capture-MS Homo sapiens
56 EXD2  
Proximity Label-MS Homo sapiens
57 ABHD14A  
Affinity Capture-MS Homo sapiens
58 SLC25A46 91137
Proximity Label-MS Homo sapiens
59 HSPA2 3306
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TRABD is involved
No pathways found





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