Gene description for GFOD2
Gene name glucose-fructose oxidoreductase domain containing 2
Gene symbol GFOD2
Other names/aliases -
Species Homo sapiens
 Database cross references - GFOD2
ExoCarta ExoCarta_81577
Vesiclepedia VP_81577
Entrez Gene 81577
HGNC 28159
UniProt Q3B7J2  
 GFOD2 identified in sEVs derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for GFOD2
Molecular Function
    nucleotide binding GO:0000166 IEA
    oxidoreductase activity GO:0016491 IEA
Biological Process
    extracellular matrix organization GO:0030198 IBA
Subcellular Localization
    extracellular region GO:0005576 IEA
    extracellular matrix GO:0031012 IBA
 Experiment description of studies that identified GFOD2 in sEVs
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for GFOD2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TXLNA 200081
Affinity Capture-MS Homo sapiens
2 GFOD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 EPHA2 1969
Proximity Label-MS Homo sapiens
4 NKIRAS2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GFOD2 is involved
No pathways found





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