Gene description for Actn1
Gene name	actinin, alpha 1
Gene symbol	Actn1
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Actn1
ExoCarta	ExoCarta_81634
Vesiclepedia	VP_81634
Entrez Gene	81634
UniProt	Q9Z1P2
Actn1 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041
Hepatocytes	19367702
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Actn1

Molecular Function     double-stranded RNA binding GO:0003725 IEA     double-stranded RNA binding GO:0003725 ISO     actin binding GO:0003779 IEA     integrin binding GO:0005178 IEA     integrin binding GO:0005178 ISO     calcium ion binding GO:0005509 IEA     protein binding GO:0005515 IPI     cytoskeletal regulatory protein binding GO:0005519 IPI     vinculin binding GO:0017166 ISO     vinculin binding GO:0017166 ISS     protein domain specific binding GO:0019904 IPI     nuclear receptor coactivator activity GO:0030374 IEA     nuclear receptor coactivator activity GO:0030374 ISO     protein homodimerization activity GO:0042803 ISO     protein homodimerization activity GO:0042803 ISS     transmembrane transporter binding GO:0044325 IEA     transmembrane transporter binding GO:0044325 ISO     actin filament binding GO:0051015 IBA     actin filament binding GO:0051015 IEA     actin filament binding GO:0051015 ISO     alpha-actinin binding GO:0051393 ISS     structural constituent of postsynapse GO:0099186 IEA     structural constituent of postsynapse GO:0099186 ISO Biological Process     actin filament organization GO:0007015 ISO     actin cytoskeleton organization GO:0030036 IBA     platelet activation GO:0030168 ISO     platelet formation GO:0030220 IEA     platelet formation GO:0030220 ISO     platelet morphogenesis GO:0036344 ISO     sarcomere organization GO:0045214 ISS     positive regulation of DNA-templated transcription GO:0045893 IEA     focal adhesion assembly GO:0048041 IEA     focal adhesion assembly GO:0048041 ISO     skeletal muscle fiber development GO:0048741 ISS     actin filament bundle assembly GO:0051017 IEA     actin filament bundle assembly GO:0051017 ISO     actin filament network formation GO:0051639 IEA     actin filament network formation GO:0051639 ISO     muscle cell development GO:0055001 IBA     platelet aggregation GO:0070527 ISO     postsynapse organization GO:0099173 IEA Subcellular Localization     stress fiber GO:0001725 IBA     stress fiber GO:0001725 IDA     stress fiber GO:0001725 ISO     stress fiber GO:0001725 ISS     ruffle GO:0001726 IEA     ruffle GO:0001726 ISO     ruffle GO:0001726 ISS     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 ISO     cytosol GO:0005829 TAS     cytoskeleton GO:0005856 IDA     cytoskeleton GO:0005856 IEA     actin filament GO:0005884 IEA     actin filament GO:0005884 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 IEA     brush border GO:0005903 IEA     brush border GO:0005903 ISO     cell-cell junction GO:0005911 ISO     zonula adherens GO:0005915 ISS     fascia adherens GO:0005916 IEA     fascia adherens GO:0005916 ISO     bicellular tight junction GO:0005923 ISS     focal adhesion GO:0005925 ISO     focal adhesion GO:0005925 ISS     actin cytoskeleton GO:0015629 IEA     lateral plasma membrane GO:0016328 ISS     sarcomere GO:0030017 ISO     Z disc GO:0030018 IBA     Z disc GO:0030018 IEA     Z disc GO:0030018 ISO     Z disc GO:0030018 ISS     lamellipodium GO:0030027 ISS     cell junction GO:0030054 IBA     cell junction GO:0030054 IDA     smooth muscle dense body GO:0030486 ISS     cortical actin cytoskeleton GO:0030864 IBA     cortical actin cytoskeleton GO:0030864 IDA     cell leading edge GO:0031252 ISS     sarcolemma GO:0042383 ISS     cell projection GO:0042995 IBA     cell projection GO:0042995 ISO     dendritic spine GO:0043197 IDA     synapse GO:0045202 IDA     anchoring junction GO:0070161 IEA     outer dense plaque of desmosome GO:0090636 ISS     inner dense plaque of desmosome GO:0090637 ISS     dense body GO:0097433 ISS     postsynaptic actin cytoskeleton GO:0098871 IDA     postsynaptic actin cytoskeleton GO:0098871 IMP     glutamatergic synapse GO:0098978 IEA     glutamatergic synapse GO:0098978 ISO     terminal web GO:1990357 ISS