Gene description for Gmfb
Gene name glia maturation factor, beta
Gene symbol Gmfb
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Gmfb
ExoCarta ExoCarta_81661
Vesiclepedia VP_81661
Entrez Gene 81661
UniProt Q63228  
 Gmfb identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Gmfb
Molecular Function
    actin binding GO:0003779 IEA
    growth factor activity GO:0008083 IEA
    Arp2/3 complex binding GO:0071933 IBA
    Arp2/3 complex binding GO:0071933 IEA
Biological Process
    signal transduction GO:0007165 IEA
    learning GO:0007612 ISO
    locomotory behavior GO:0007626 ISO
    negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316 IBA
    actin filament debranching GO:0071846 IBA
    actin filament debranching GO:0071846 IEA
Subcellular Localization
    cortical actin cytoskeleton GO:0030864 IBA
 Experiment description of studies that identified Gmfb in sEVs
1
Experiment ID 95
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Gmfb
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Itm2b 290364
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Gmfb is involved
No pathways found





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