Gene description for TRPT1
Gene name tRNA phosphotransferase 1
Gene symbol TRPT1
Other names/aliases -
Species Homo sapiens
 Database cross references - TRPT1
ExoCarta ExoCarta_83707
Vesiclepedia VP_83707
Entrez Gene 83707
HGNC 20316
MIM 610470
UniProt Q86TN4  
 TRPT1 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for TRPT1
Molecular Function
    tRNA 2'-phosphotransferase activity GO:0000215 IBA
    protein binding GO:0005515 IPI
Biological Process
    tRNA splicing, via endonucleolytic cleavage and ligation GO:0006388 IBA
 Experiment description of studies that identified TRPT1 in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TRPT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 STRIP1 85369
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 EEFSEC 60678
Co-fractionation Homo sapiens
4 SERPINA10 51156
Affinity Capture-MS Homo sapiens
5 GAPDHS 26330
Affinity Capture-MS Homo sapiens
6 TRAF2 7186
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
7 DYNC1LI1 51143
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 Nedd4 25489
Biochemical Activity Rattus norvegicus
9 TP53 7157
Negative Genetic Homo sapiens
10 ZYG11B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 GORASP2 26003
Two-hybrid Homo sapiens
12 TEX19  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TRPT1 is involved
No pathways found





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