Gene description for ARMC10
Gene name armadillo repeat containing 10
Gene symbol ARMC10
Other names/aliases PNAS-112
PNAS112
PSEC0198
SVH
Species Homo sapiens
 Database cross references - ARMC10
ExoCarta ExoCarta_83787
Vesiclepedia VP_83787
Entrez Gene 83787
HGNC 21706
MIM 611864
UniProt Q8N2F6  
 ARMC10 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for ARMC10
Molecular Function
    p53 binding GO:0002039 IPI
    protein binding GO:0005515 IPI
    DNA binding domain binding GO:0050692 IDA
Biological Process
    positive regulation of growth rate GO:0040010 IDA
    negative regulation of apoptotic process GO:0043066 IDA
    negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902254 IMP
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial outer membrane GO:0005741 IEA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
 Experiment description of studies that identified ARMC10 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ARMC10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CAPNS2 84290
Two-hybrid Homo sapiens
2 MTCH1 23787
Proximity Label-MS Homo sapiens
3 PARP1 142
Proximity Label-MS Homo sapiens
4 IGHG4 3503
Affinity Capture-MS Homo sapiens
5 PXMP2  
Proximity Label-MS Homo sapiens
6 MME 4311
Affinity Capture-MS Homo sapiens
7 ACTA2 59
Affinity Capture-MS Homo sapiens
8 MYO18A 399687
Affinity Capture-MS Homo sapiens
9 MTCH2 23788
Proximity Label-MS Homo sapiens
10 FKBP8 23770
Proximity Label-MS Homo sapiens
11 IGHG2 3501
Affinity Capture-MS Homo sapiens
12 RHOT2 89941
Proximity Label-MS Homo sapiens
13 FAM25C  
Two-hybrid Homo sapiens
14 TCEA2  
Two-hybrid Homo sapiens
15 OCIAD1 54940
Proximity Label-MS Homo sapiens
16 APEX1 328
Affinity Capture-RNA Homo sapiens
17 PPP1R9A  
Affinity Capture-MS Homo sapiens
18 FAM25A  
Two-hybrid Homo sapiens
19 FAM25G  
Two-hybrid Homo sapiens
20 FIS1 51024
Proximity Label-MS Homo sapiens
21 COQ9  
Affinity Capture-MS Homo sapiens
22 RNF166  
Affinity Capture-MS Homo sapiens
23 POTEKP 440915
Affinity Capture-MS Homo sapiens
24 AHNAK2 113146
Affinity Capture-MS Homo sapiens
25 RAB5C 5878
Proximity Label-MS Homo sapiens
26 LHFPL5  
Affinity Capture-MS Homo sapiens
27 AKAP1 8165
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ARMC10 is involved
No pathways found





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