Gene description for SNX25
Gene name
sorting nexin 25
Gene symbol
SNX25
Other names/aliases
MSTP043 SBBI31
Species
Homo sapiens
Database cross references - SNX25
ExoCarta
ExoCarta_83891
Vesiclepedia
VP_83891
Entrez Gene
83891
HGNC
21883
UniProt
Q9H3E2
SNX25 identified in sEVs derived from the following tissue/cell type
Malignant pleural effusions
14975938
Neuroblastoma cells
25944692
Gene ontology annotations for SNX25
Experiment description of studies that identified SNX25 in sEVs
1
Experiment ID
51
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|MHCII
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
14975938
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes isolated from human malignant pleural effusions.
Authors
"Bard MP, Hegmans JP, Hemmes A, Luider TM, Willemsen R, Severijnen LA, van Meerbeeck JP, Burgers SA, Hoogsteden HC, Lambrecht BN"
Journal name
AJRCMB
Publication year
2004
Sample
Malignant pleural effusions
Sample name
Pleural Fluid - Breast cancer
Isolation/purification methods
Differential centrifugation Sucrose density gradient
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [MALDI TOF] Western blotting
2
Experiment ID
224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25944692
Organism
Homo sapiens
Experiment description
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors
"Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name
Oncotarget
Publication year
2015
Sample
Neuroblastoma cells
Sample name
SH-SY5Y
Isolation/purification methods
Differential centrifugation Ultracentrifugation OptiPrep density gradient
Flotation density
1.10 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Western blotting
Protein-protein interactions for SNX25
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
ZDHHC12
Affinity Capture-MS
Homo sapiens
2
ATP6V0D1
9114
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
COA3
28958
Affinity Capture-MS
Homo sapiens
4
GJA8
Affinity Capture-MS
Homo sapiens
5
TSPAN5
10098
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
6
GJA3
Affinity Capture-MS
Homo sapiens
7
TSPAN15
23555
Affinity Capture-MS
Homo sapiens
8
NDUFC2
4718
Affinity Capture-MS
Homo sapiens
9
B4GAT1
11041
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
10
VAPB
9217
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
11
HSP90B1
7184
Cross-Linking-MS (XL-MS)
Homo sapiens
12
GBA
2629
Affinity Capture-MS
Homo sapiens
13
APH1A
51107
Affinity Capture-MS
Homo sapiens
14
TTYH1
Affinity Capture-MS
Homo sapiens
15
SIX5
Co-fractionation
Homo sapiens
View the network
image/svg+xml
Pathways in which SNX25 is involved
No pathways found