Gene description for Slc25a4
Gene name	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
Gene symbol	Slc25a4
Other names/aliases	Ant1
Species	Rattus norvegicus
Database cross references - Slc25a4
ExoCarta	ExoCarta_85333
Vesiclepedia	VP_85333
Entrez Gene	85333
UniProt	Q05962
Slc25a4 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Slc25a4

Molecular Function     ATP:ADP antiporter activity GO:0005471 IEA     ATP:ADP antiporter activity GO:0005471 ISO     ATP:ADP antiporter activity GO:0005471 ISS     protein binding GO:0005515 IPI     proton transmembrane transporter activity GO:0015078 IEA     proton transmembrane transporter activity GO:0015078 ISO     oxidative phosphorylation uncoupler activity GO:0017077 IEA     oxidative phosphorylation uncoupler activity GO:0017077 ISO     oxidative phosphorylation uncoupler activity GO:0017077 ISS     enzyme binding GO:0019899 IPI Biological Process     liver development GO:0001889 IEP     heart development GO:0007507 IEP     apoptotic mitochondrial changes GO:0008637 IEA     apoptotic mitochondrial changes GO:0008637 ISO     negative regulation of cardiac muscle cell apoptotic process GO:0010667 IDA     ADP transport GO:0015866 ISO     ADP transport GO:0015866 ISS     regulation of mitochondrial membrane permeability GO:0046902 IEA     regulation of mitochondrial membrane permeability GO:0046902 ISO     negative regulation of necroptotic process GO:0060546 IEA     negative regulation of necroptotic process GO:0060546 ISO     positive regulation of cell growth involved in cardiac muscle cell development GO:0061051 IDA     response to interleukin-1 GO:0070555 IEP     mitochondrial ADP transmembrane transport GO:0140021 IEA     mitochondrial ADP transmembrane transport GO:0140021 ISO     mitochondrial ADP transmembrane transport GO:0140021 ISS     negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901029 IBA     positive regulation of mitophagy GO:1901526 IEA     positive regulation of mitophagy GO:1901526 ISO     positive regulation of mitophagy GO:1901526 ISS     negative regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902109 IDA     proton transmembrane transport GO:1902600 IEA     mitochondrial ATP transmembrane transport GO:1990544 IEA     mitochondrial ATP transmembrane transport GO:1990544 ISO     mitochondrial ATP transmembrane transport GO:1990544 ISS     adaptive thermogenesis GO:1990845 IEA     adaptive thermogenesis GO:1990845 ISO     adaptive thermogenesis GO:1990845 ISS     positive regulation of oxidative phosphorylation uncoupler activity GO:2000277 IMP Subcellular Localization     mitochondrion GO:0005739 ISO     mitochondrial outer membrane GO:0005741 IDA     mitochondrial inner membrane GO:0005743 IDA     mitochondrial inner membrane GO:0005743 IEA     mitochondrial inner membrane GO:0005743 ISO     mitochondrial permeability transition pore complex GO:0005757 IEA     mitochondrial permeability transition pore complex GO:0005757 ISO     mitochondrial permeability transition pore complex GO:0005757 ISS     membrane GO:0016020 ISO     mitochondrial membrane GO:0031966 ISS     membrane raft GO:0045121 IDA