Gene description for CD163
Gene name CD163 molecule
Gene symbol CD163
Other names/aliases M130
MM130
Species Homo sapiens
 Database cross references - CD163
ExoCarta ExoCarta_9332
Vesiclepedia VP_9332
Entrez Gene 9332
HGNC 1631
MIM 605545
UniProt Q86VB7  
 CD163 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CD163
Molecular Function
    scavenger receptor activity GO:0005044 NAS
    protein binding GO:0005515 IPI
    scaffold protein binding GO:0097110 IPI
Biological Process
    acute-phase response GO:0006953 IEA
    vesicle-mediated transport GO:0016192 IEA
Subcellular Localization
    extracellular region GO:0005576 TAS
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    external side of plasma membrane GO:0009897 IBA
    external side of plasma membrane GO:0009897 IDA
    endocytic vesicle membrane GO:0030666 TAS
 Experiment description of studies that identified CD163 in sEVs
1
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD163
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FCGR1A  
Two-hybrid Homo sapiens
2 CSNK2B 1460
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
3 ATP4A 495
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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