Gene description for Scamp3
Gene name secretory carrier membrane protein 3
Gene symbol Scamp3
Other names/aliases Sc3
TU52
Species Mus musculus
 Database cross references - Scamp3
ExoCarta ExoCarta_24045
Vesiclepedia VP_24045
Entrez Gene 24045
UniProt O35609  
 Scamp3 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Scamp3
Molecular Function
    ubiquitin protein ligase binding GO:0031625 ISO
Biological Process
    intracellular protein transport GO:0006886 TAS
    protein transport GO:0015031 IBA
    response to retinoic acid GO:0032526 IDA
Subcellular Localization
    Golgi membrane GO:0000139 IDA
    trans-Golgi network membrane GO:0032588 IBA
    intracellular membrane-bounded organelle GO:0043231 ISO
    recycling endosome membrane GO:0055038 IBA
 Experiment description of studies that identified Scamp3 in sEVs
1
Experiment ID 907
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Scamp3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Rpa1 68275
Co-fractionation Mus musculus
2 Fancd2  
Affinity Capture-MS Mus musculus
3 Scamp1  
Co-fractionation Mus musculus
4 Tmem173  
Proximity Label-MS Mus musculus
View the network image/svg+xml
 Pathways in which Scamp3 is involved
No pathways found





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